Elemental diet is an effective treatment for eosinophilic esophagitis in children and adolescents.

TL;DR: No pathognomonic features have been identified for EoE and its diagnosis must be made on both clinical and histological grounds, so effective treatments rely on steroids and dietary exclusions.

TL;DR: This study identified five epithelial-derived markers differentially expressed in eosinophilic esophagitis easily detectable by immunohistochemistry with potential diagnostic utility.

TL;DR: A broad framework for recognizing the remarkable variety of clinical manifestations of eosinophilic esophagitis in children is provided, which must be considered as part of the differential diagnosis in many different clinical situations.

TL;DR: This review will highlight the treatments of EE in children and adults, and outline the limitations in the current studies and suggest seven major issues in the study design that must be addressed in future drug trials.

TL;DR: The presence of high concentrations of IEE in esophageal biopsies from patients with dysphagia, normal endoscopy, and normal 24-hr esophagal pH monitoring represents a distinctive clinicopathologic syndrome not previously described.

TL;DR: It is concluded that basal cell hyperplasia of the squamous epithelium and location of the papillae close to the epithelial surface are the histological consequences of gastroesophageal reflux.

TL;DR: Pediatric patients in a series with marked esophageal eosinophilia and chronic symptoms of gastroesphageal reflux disease unresponsive to aggressive medical antireflux therapy had both clinical and histologic improvement after oral corticosteroid therapy.

TL;DR: The spectrum of pediatric eosinophilic esophagitis beyond infancy: a clinical series of 30 children shows marked variation in the severity of the disease in children aged four to six months.