What caused the dissociation of the aqueous ICs?

The trans–cis isomerization of azobenzene triggered by UV light caused a signicant change in the AAB molecular geometry and subsequently the dissociation from the ICs.

What caused the ICs to be enlarged?

UV irradiation during electrospinning ight demonstrated interruption of the ICs and consequently broader diameter distributions were obtained.

What caused the lower pressure in the cavity-on-bead structure?

The lower water content in the CD cavities builds up a lower inner pressure during electrospinning, which caused the cavity-on-bead structure at a low concentration of ICs.

Why is the cavity-on-bead structure in Mat The authorso low?

The cavity-on-bead structure in Mat The authoris probably due to that the lower inner pressure compared to ambient spinning conditions has built up from the CD ICs system which has a lower water content in the CD cavities.

What is the effect of UV irradiation on the surface of the ber?

Post-spinning UV irradiation induced topography and adhesion force changes on the electrospun nanober surfaces, revealed by in situ AFM quantitative nanomechanical mapping.

What was the effect of the UV irradiation on the ICs?

Thus electrospinning became unstable and the resulting beads (Mat UV-I and Mat UV-II) or bers (Mat UV-III) demonstrated broader diameter distributions.

What were the structural analyses of the electrospun ICs?

Thermophysical properties of the electrospun ICs were studied by TGA and DSC, while the structural analyses were performed by FTIR and XRD.

What is the role of azobenzene in the ion channel?

8Light-responsive azobenzene has been found to be able to form inclusion complexes (ICs) with CDs in its trans state,9 while its cis form is too bulky.

What is the chemical mapping of the HPbCD and AAB nanobers?

The TOF-SIMS chemical mapping results show that the ICs were homogeneously distributed and randomly oriented without preferential allocation.

Open AccessJournal Article10.1039/C2TC00180B

Electrospun UV-responsive supramolecular nanofibers from a cyclodextrin–azobenzene inclusion complex

Menglin Chen, +6 more

- 28 Jan 2013

- Journal of Materials Chemistry C

- Vol. 1, Iss: 4, pp 850-855

TL;DR: In this paper, the IC of 4-aminoazobenzene (AAB) and hydroxypropyl-β-cyclodextrin (HPβCD), with its inherent viscosity from hydrogen bondings between CDs and π-π stacking between AABs, was electrospun into nanofibers from water without using any carrier polymer matrix.

Abstract: A combination of the unique hosting properties of cyclodextrins (CDs) and the peculiar UV-responsive trans–cis isomerization of the guest molecule azobenzene has endowed light-responsibility of the inclusion complex (IC). The IC of 4-aminoazobenzene (AAB) and hydroxypropyl-β-cyclodextrin (HPβCD), with its inherent viscosity from hydrogen bondings between CDs and π–π stacking between AABs, was electrospun into nanofibers from water without using any carrier polymer matrix. The integrity of electrospun ICs was proven by thermogravimetric analysis (TGA), differential scanning calorimetry (DSC), together with Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). The homogeneous distribution of HPβCD–AAB-IC was confirmed by surface chemistry mapping using time-of-flight secondary ion mass spectrometry (ToF-SIMS). The UV response of ICs prior to, during and post electrospinning was investigated. UV irradiation prior to electrospinning caused precipitation of AAB from the aqueous IC solution. UV irradiation during electrospinning flight demonstrated the interruption of ICs and consequently broader diameter distributions were obtained. Post-spinning UV irradiation induced topography and adhesion force changes on the electrospun nanofiber surfaces, demonstrated by in situ atomic force microspectroscopy (AFM) quantitative nanomechanical mapping. The present study is the first case where the supramolecule with stimuli response was electrospun into nanofibers with retained activity.

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Most frequently asked questions

1. What have the authors contributed in "Electrospun uv-responsive supramolecular nanofibers from a cyclodextrin–azobenzene inclusion complex†" ?

The UV response of ICs prior to, during and post electrospinning was investigated.. The present study is the first case where the supramolecule with stimuli response was electrospun into nanofibers with retained activity.

2. What are the future works in "Electrospun uv-responsive supramolecular nanofibers from a cyclodextrin–azobenzene inclusion complex†" ?

Further study based on their previous study7d and CD prodrug in this direction is currently underway.. Furthermore, the present novel ndings again proved the simplicity, robustness, and versatility of the electrospinning technique, extending its great potential in a broad range of research areas.

3. What is the effect of UV irradiation on the ICs?

UV irradiation triggers the photoisomerization of AAB from the trans form to its cis form, and consequently the dissociation of the HPbCD–AAB-ICs.

4. What is the role of azobenzenes in the uid?

It is crucial to the presence of polymer chain entanglements in the charged uid that ensures the uid does not break up into dropletsbut formsa stable jetwhen theelectrostatic repulsive forceson the uid surface overcome the surface tension.

Table 2 Peak assignments derived from the positive ion ToF-SIMS spectra in Fig. 2

Fig. 4 (a) TGA spectra of the electrospun HPbCD–AAB-IC Mat III and the components AAB and HPbCD, (b) DSC spectra of the electrospun HPbCD–AAB-IC Mat III and AAB.

Fig. 3 ToF-SIMS chemical images of the HPbCD–AAB-IC Mats I (upper panel, area: 50 mm 50 mm) and Mat IV (lower panel, area 500 mm 500 mm). Column (a): HPbCD fragment ion images; column (b): AAB fragment ion images; and column (c): overlay images of column (a) and column (b).

Table 1 Electrospinning of HPbCD–AAB-ICs

Fig. 1 SEM images of electrospun HPbCD–AAB-ICs.

Fig. 5 AFM quantitative nanomechanical mapping of the HPbCD–AAB-IC Mat IV before and after UV irradiation. (A): The overview of the fiber; the inset square indicates the position where AFM nanomechanical maps are recorded; (B and E): the topography images before and after UV exposure; (D): the horizontal line profiles across (B and E); (C and F): the corresponding tip–sample adhesion maps of (B and E) respectively; (G): the tip–sample adhesion force distribution before (10.66 0.63 nN) and after UV exposure (5.91 0.42 nN).

Citations

Journal Article•10.1016/J.PMATSCI.2021.100869

Cyclodextrin-based nanostructures

Ganesh Narayanan, +6 more

- 05 Oct 2021

- Progress in Materials Science

TL;DR: In this paper, the authors summarized researches on the presence of CDs in various aspects of nanotechnology ranging from nanoparticles, nanorods, nanomicelles, to nanofibers, and provided state-of-the-art applications that are being carried out using these nanostructures.

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Journal Article•10.1016/J.CARBPOL.2021.118042

Polymer-free cyclodextrin and natural polymer-cyclodextrin electrospun nanofibers: A comprehensive review on current applications and future perspectives

Andrea Dodero, +4 more

- 15 Jul 2021

- Carbohydrate Polymers

TL;DR: In this paper, the use of cyclodextrins and their derivatives to prepare electrospun nanofibers with specific features is discussed and the advantages and disadvantages of such approaches and their possible applications are investigated along with the current limitations in the exploitation of electrospinning at the industrial level.

...read moreread less

Journal Article•10.1039/C3NR06197C

Ultraporous interweaving electrospun microfibers from PCL–PEO binary blends and their inflammatory responses

Yan-Fang Li, +8 more

- 27 Feb 2014

- Nanoscale

TL;DR: It is reported for the first time that a nanoscale immiscible polymer blend solution electrojet can assemble into ultraporous interweaving microfibers, an intriguingly novel morphology originated from a blend of polycaprolactone and polyethylene oxide in a DCM-DMF mixed solution.

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•Journal Article•10.3390/MOLECULES22020230

Electrospun Fibers of Cyclodextrins and Poly(cyclodextrins)

Alejandro Costoya, +2 more

- 03 Feb 2017

- Molecules

TL;DR: The aim of this review is to provide an overview of the state-of-the-art on CD-containing electrospun mats, including possibilities of development of stimuli-responsive fibers.

...read moreread less

Journal Article•10.1021/MA501100R

Hierarchical Assembly of Amphiphilic POSS-Cyclodextrin Molecules and Azobenzene End-Capped Polymers

Jinze Li, +4 more

- 14 Aug 2014

- Macromolecules

TL;DR: In this article, a smart multistimuli responsive system was prepared through a light controlled supramolecular assembly, where the authors showed that the trans-azo end groups of the PPA interacted with the cyclodextrin cavities on the nanosphere, and complex micelles were formed by the supersramolecula.

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...

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References

Journal Article•10.1039/C2RA01311H

Direct force producing uniform ultra-thin chitosan films by atomic force microscopy

Huiling Zhao, +6 more

- 13 Mar 2012

- RSC Advances

TL;DR: In this paper, the fabrication of uniform ultra-thin chitosan films with a thickness of several nanometres using a two-step physical approach with the help of spin coating and mechanical manipulation is described.

...read moreread less

Journal Article•10.1039/B415946B

Assembly behavior of inclusion complexes of β-cyclodextrin with 4-hydroxyazobenzene and 4-aminoazobenzene

Yu Liu, +3 more

- 09 Feb 2005

- Organic and Biomolecular Chemistry

TL;DR: The combination of crystallographic and spectral investigations jointly revealed the inclusion complexation geometry of beta-CD with 4-hydroxyazobenzene and 4-aminoazobzene in both solution and the solid state, which demonstrated that the disparity of substituents in the azobenzenes played an important role in theclusion complexation and molecular assembly.

...read moreread less

Journal Article•10.1002/ADMA.201101806

Design of a Cellular‐Uptake‐Shielding “Plug and Play” Template for Photo Controllable Drug Release

Wang Xiao, +6 more

- 16 Aug 2011

- Advanced Materials

TL;DR: A novel light-responsive “plug and play” (PnP) polyanionic template as drug delivery system, which can inhibit the endocytosis of antineoplastic drug for normal tissues, and can be simultaneously loaded and unloaded onto the template.

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•Journal Article•10.1073/PNAS.0909444107

Controlling the enzymatic activity of a restriction enzyme by light.

Benno Schierling, +10 more

- 26 Jan 2010

- Proceedings of the National Academy of S...

TL;DR: Modulating the activity of a restriction enzyme with light by cross-linking two suitably located cysteine residues with a bifunctional azobenzene derivative, which can adopt a cis- or trans-configuration when illuminated by UV or blue light, respectively, enzymatic activity can be controlled in a reversible manner.

...read moreread less

Journal Article•10.1021/LA052878F

Self-Assembly of β-Cyclodextrin in Water. Part 1: Cryo-TEM and Dynamic and Static Light Scattering

Massimo Bonini, +5 more

- 05 Jan 2006

- Langmuir

TL;DR: A critical aggregation concentration between 2 and 3 mM was determined by using dynamic (DLS) and static (SLS) light scattering to investigate the presence of β-cyclodextrin aggregates in water.

...read moreread less

...

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Electrospun UV-responsive supramolecular nanofibers from a cyclodextrin–azobenzene inclusion complex

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AI Agents for this Paper

Most frequently asked questions

1. What have the authors contributed in "Electrospun uv-responsive supramolecular nanofibers from a cyclodextrin–azobenzene inclusion complex†" ?

2. What are the future works in "Electrospun uv-responsive supramolecular nanofibers from a cyclodextrin–azobenzene inclusion complex†" ?

3. What is the effect of UV irradiation on the ICs?

4. What is the role of azobenzenes in the uid?

5. What caused the dissociation of the aqueous ICs?

6. What caused the ICs to be enlarged?

7. What caused the lower pressure in the cavity-on-bead structure?

8. Why is the cavity-on-bead structure in Mat The authorso low?

9. What is the effect of UV irradiation on the surface of the ber?

10. What was the effect of the UV irradiation on the ICs?

11. What were the structural analyses of the electrospun ICs?

12. What is the role of azobenzene in the ion channel?

13. What is the chemical mapping of the HPbCD and AAB nanobers?

Figures

Citations

Cyclodextrin-based nanostructures

Polymer-free cyclodextrin and natural polymer-cyclodextrin electrospun nanofibers: A comprehensive review on current applications and future perspectives

Ultraporous interweaving electrospun microfibers from PCL–PEO binary blends and their inflammatory responses

Electrospun Fibers of Cyclodextrins and Poly(cyclodextrins)

Hierarchical Assembly of Amphiphilic POSS-Cyclodextrin Molecules and Azobenzene End-Capped Polymers

References

Direct force producing uniform ultra-thin chitosan films by atomic force microscopy

Assembly behavior of inclusion complexes of β-cyclodextrin with 4-hydroxyazobenzene and 4-aminoazobenzene

Design of a Cellular‐Uptake‐Shielding “Plug and Play” Template for Photo Controllable Drug Release

Controlling the enzymatic activity of a restriction enzyme by light.

Self-Assembly of β-Cyclodextrin in Water. Part 1: Cryo-TEM and Dynamic and Static Light Scattering

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