Journal Article10.1016/J.DIABRES.2008.05.003
Effect of fasting on PPARγ and AMPK activity in adipocytes
Kazuo Kajita,Tomoatsu Mune,Takahide Ikeda,Masami Matsumoto,Yoshihiro Uno,Chiyo Sugiyama,Kenji Matsubara,Hiroyuki Morita,Masao Takemura,Mitsuru Seishima,Jun Takeda,Tatsuo Ishizuka +11 more
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TL;DR: Overnight fasting increased the AMP/ATP ratio and AMP-activated protein kinase (AMPK) in adipose tissue, but not in muscle or liver tissue, and the effect of 5-aminoimidazole-4-carboxyamide-ribonucleoside (AICAR) on PPARgamma expression in primary cultured adipocytes was investigated.
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About: This article is published in Diabetes Research and Clinical Practice. The article was published on 01 Aug 2008. The article focuses on the topics: AMPK & Adipose tissue.
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Citations
Distinct but complementary contributions of PPAR isotypes to energy homeostasis
TL;DR: This Review discusses the complementary and distinct metabolic effects of the PPAR isotypes together with the underlying cellular and molecular mechanisms, as well as the synthetic PPAR ligands that are used in the clinic or under development.
Nutrient-dependent Regulation of PGC-1α’s Acetylation State and Metabolic Function Through the Enzymatic Activities of Sirt1/GCN5
TL;DR: This review evaluates how the nutrient regulation of PGC-1alpha activity squares with the regulation of its acetylation state by the deacetylase Sirt1 and the acetyltransferase GCN5 and proposes an outline of additional experimental directives that will help to shed additional light on this very powerful transcriptional coactivator.
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PPARs as Nuclear Receptors for Nutrient and Energy Metabolism.
TL;DR: The complex roles of PPARs in metabolic networks keep these factors in the forefront of research because it is hoped that they will have potential therapeutic effects in future applications.
180
Time-restricted eating effects on performance, immune function, and body composition in elite cyclists: a randomized controlled trial
Tatiana Moro,Grant M. Tinsley,Giovanni Antonio Longo,Davide Grigoletto,Antonino Bianco,Cinzia Ferraris,Monica Guglielmetti,Alessandro Veneto,Anna Tagliabue,Giuseppe Marcolin,Antonio Paoli +10 more
TL;DR: In this paper, the effects of a particular intermittent fasting approach, called time-restricted eating (TRE), during 4 weeks of high-level endurance training were investigated, and the results suggest that a TRE program with an 8-h feeding window elicits weight loss, improves body composition and increases PPO/BW in elite cyclists.
Cellular mechanisms regulating fuel metabolism in mammals: Role of adipose tissue and lipids during prolonged food deprivation
Jose A. Viscarra,Rudy M. Ortiz +1 more
TL;DR: These processes are described in greater detail and the extent to which adipose tissue and lipid substrates regulate metabolism in food deprived mammals is explored with comments on future directions to better assess the contribution of adiposes tissue to metabolism.
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