Journal Article10.1080/09513590701807431
Effect of Aerodiol administration on ocular arteries in postmenopausal women
Figen Kir Sahin,Gülengül Köken,Emine Coşar,Dagistan Tolga Arioz,Bumin Degirmenci,Ramazan Albayrak,Murat Acar +6 more
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TL;DR: Nal 17β-estradiol administration in postmenopausal women causes an improvement in the ocular vascular Doppler indices, suggesting that there could be a positive effect of Aerodiol® on middle-sized arteries and arterioles.
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Abstract: Objective. The aim of the present study was to evaluate the alteration of ocular blood hemodynamics after intranasal administration of 17β-estradiol, through measurement of the ophthalmic artery (OA) and the central retinal artery (CRA) using color duplex sonography.Methods. Thirty healthy women who had been naturally postmenopausal for at least 1 year were enrolled in the study. A randomized, placebo-controlled, crossover, double-blinded study was conducted of the acute effect of 17β-estradiol (Aerodiol®; Servier, Chambrayles-Tours, France) on OA and CRA blood flow using color duplex sonography.Results. The peak systolic and end diastolic velocities of the CRA were increased significantly after 17β-estradiol administration compared with placebo. A significant decrease was also found in the pulsatility and resistive indices of the CRA. However, there were no statistically significant differences in OA flow velocities or pulsatility and resistive indices.Conclusions. Nasal 17β-estradiol administration in p...
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Pregnancy and Glaucoma
TL;DR: In managing the pregnant glaucoma patient with medical therapy, one must consider not only the systemic side effects on the mother, but also any potentially harmful effects onThe developing fetus.
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Ophthalmic artery vasodilation after intranasal estradiol use in postmenopausal women.
Marco Matteo Ciccone,Ettore Cicinelli,Alessio Giovanni,Pietro Scicchitano,Michele Gesualdo,Annapaola Zito,Fara Fornarelli,Manuela Locorotondo,Maria Vittoria Cicinelli,Concetta Di Teo,Giuseppe Farinola,Domenico Scrutinio +11 more
TL;DR: Administration of a single dose of intranasal 17-beta-estradiol to healthy postmenopausal women increases ophthalmic artery perfusion.
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WS04‐04Vascular impedance of uterine, inferior vesicle and ophthalmic arteries in postmenopausal women receiving hormonal replacement therapy: comparative Doppler study
TL;DR: In this article, the effects of combined hormone replacement therapy (HRT) on the vascular impedance of the uterine, inferior vesicle, and ophtalmic artery were investigated.
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Evaluation of retinal and choroidal microvascular changes in healthy pregnant women using optical coherence
Esat Çinar,Berna Yüce,Cem Küçükdönmez +2 more
- 01 Jan 2020
TL;DR: Superfi cial and deep vessel densities were signifi cantly greater in the pregnant women than controls in all areas (foveal, parafoveAL, temporal, superior, nasal, inferior) (P<0.05 for all).
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Transient Monocular Vision Loss on Awakening: A Benign Amaurotic Phenomenon
Marc A. Bouffard,Wayne T. Cornblath,Joseph F. Rizzo,Michael S. Lee,Lindsey B. Delott,Eric R. Eggenberger,Nurhan Torun +6 more
TL;DR: Evaluation was uniformly negative when patients described waking with isolated vision loss in 1 eye with subsequent resolution, usually in less than 15 minutes, suggesting this visual phenomenon may represent an autoregulatory failure resulting in a supply/demand mismatch during low-light conditions.
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