EASL-EASD-EASO Clinical Practice Guidelines for the Management of Non-Alcoholic Fatty Liver Disease
Giulio Marchesini,Christopher P. Day,Jean-François Dufour,Ali Canbay,Valerio Nobili,Vlad Ratziu,Herbert Tilg,Michael Roden,Amalia Gastaldelli,Hannele Yki-Järvinen,Fritz Schick,Roberto Vettor,Gema Frühbeck,Lisbeth Mathus-Vliegen +13 more
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TL;DR: The final purpose is to improve patient care and awareness of the importance of NAFLD, and to assist stakeholders in the decision-making process by providing evidence-based data, which also takes into consideration the burden of clinical management for the healthcare system.
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About: This article is published in Journal of Hepatology. The article was published on 01 May 2016. and is currently open access. The article focuses on the topics: Fatty liver & Elafibranor.
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Citations
Poor Awareness of Liver Disease Among Adults With NAFLD in the United States.
Saleh A. Alqahtani,James Paik,Rakesh Biswas,Tamoore Arshad,Linda Henry,Zobair M. Younossi +5 more
- 01 Jul 2021
TL;DR: Nearly 96% of adults with NAFLD in the United States were unaware they had liver disease, especially among young adults and non‐Hispanic Blacks, and efforts are needed to improve awareness.
92
HIF-2α upregulation mediated by hypoxia promotes NAFLD-HCC progression by activating lipid synthesis via the PI3K-AKT-mTOR pathway.
Jianxu Chen,Jiandi Chen,Jiaxin Huang,Zhanyu Li,Yihang Gong,Baojia Zou,Xialei Liu,Lei Ding,Peiping Li,Zhiquan Zhu,Baimeng Zhang,Hui Guo,Chaonong Cai,Jian Li +13 more
- 04 Dec 2019
TL;DR: In a hypoxic microenvironment, HIF-2α upregulation promotes steatotic HCC progression by activating lipid synthesis via the PI3K-AKT-mTOR pathway, which can be a biomarker and target in developing specific therapeutic measures for NAFLD-HCC patients.
Utility of Attenuation Coefficient Measurement Using an Ultrasound-Guided Attenuation Parameter for Evaluation of Hepatic Steatosis: Comparison With MRI-Determined Proton Density Fat Fraction
Toshifumi Tada,Takashi Kumada,Hidenori Toyoda,Natsuko Kobayashi,Yasuhiro Sone,Takuma Oguri,Naohisa Kamiyama +6 more
TL;DR: UGAP-determined attenuation coefficient values had a good diagnostic ability to detect hepatic steatosis in patients with chronic liver disease.
91
Randomized trial comparing effects of weight loss by liraglutide with lifestyle modification in non-alcoholic fatty liver disease.
Joan Khoo,John Chen Hsiang,Ranu Taneja,Seok-Hwee Koo,Gaik-Hong Soon,Carmen Jia Wen Kam,Ngai-Moh Law,Tiing Leong Ang +7 more
TL;DR: The effects of weight loss induced with the glucagon‐like peptide‐1 agonist liraglutide are compared with that of lifestyle modification, followed by weight maintenance after discontinuing intervention, in obese adults with non‐alcoholic fatty liver disease (NAFLD).
91
Mediterranean Diet and Multi-Ingredient-Based Interventions for the Management of Non-Alcoholic Fatty Liver Disease
Manuel Suárez,Noemí Boqué,Josep M. del Bas,Jordi Mayneris-Perxachs,Lluís Arola,Antoni Caimari +5 more
TL;DR: Current strategies for treating NAFLD and NASH based on multi-ingredient-based supplements or the Mediterranean diet, a dietary pattern rich in bioactive compounds, are reviewed.
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