Early Versus Delayed Initiation of Concurrent Palliative Oncology Care: Patient Outcomes in the ENABLE III Randomized Controlled Trial
Marie Bakitas,Tor D. Tosteson,Zhigang Li,Kathleen Doyle Lyons,Jay G. Hull,Zhongze Li,J. Nicholas Dionne-Odom,Jennifer Frost,Konstantin H. Dragnev,Mark T. Hegel,Andres Azuero,Tim A. Ahles +11 more
TL;DR: Early-entry participants' patient-reported outcomes and resource use were not statistically different; however, their survival 1-year after enrollment was improved compared with those who began 3 months later.
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Abstract: Purpose Randomized controlled trials have supported integrated oncology and palliative care (PC); however, optimal timing has not been evaluated. We investigated the effect of early versus delayed PC on quality of life (QOL), symptom impact, mood, 1-year survival, and resource use. Patients and Methods Between October 2010 and March 2013, 207 patients with advanced cancer at a National Cancer Institute cancer center, a Veterans Affairs Medical Center, and community outreach clinics were randomly assigned to receive an in-person PC consultation, structured PC telehealth nurse coaching sessions (once per week for six sessions), and monthly follow-up either early after enrollment or 3 months later. Outcomes were QOL, symptom impact, mood, 1-year survival, and resource use (hospital/intensive care unit days, emergency room visits, chemotherapy in last 14 days, and death location). Results Overall patient-reported outcomes were not statistically significant after enrollment (QOL, P = .34; symptom impact, P = ....
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References
The CES-D Scale: A Self-Report Depression Scale for Research in the General Population
TL;DR: The CES-D scale as discussed by the authors is a short self-report scale designed to measure depressive symptomatology in the general population, which has been used in household interview surveys and in psychiatric settings.
•Book
Statistical Analysis with Missing Data
Roderick J. A. Little,Donald B. Rubin +1 more
- 01 Jan 1987
TL;DR: This work states that maximum Likelihood for General Patterns of Missing Data: Introduction and Theory with Ignorable Nonresponse and large-Sample Inference Based on Maximum Likelihood Estimates is likely to be high.
18.3K
Statistical Analysis with Missing Data
TL;DR: Theory of Inference Based on the Likelihood Function.PART I: OVERVIEW AND BASIC APPROACHES.Preface.Subject Index.Author Index.
7K
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