Journal Article10.1016/S0161-6420(99)90497-9
Early Manifest Glaucoma Trial: design and baseline data.
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TL;DR: The EMGT is the first large randomized, clinical trial to evaluate the role of immediate pressure reduction, as compared to no initial reduction, in patients with early glaucoma and normal or moderately elevated IOP, and its results will have implications for the clinical management of glau coma.
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About: This article is published in Ophthalmology. The article was published on 01 Nov 1999. The article focuses on the topics: Intraocular pressure & Glaucoma.
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Citations
Baseline Vessel Density Parameters for Predicting Visual Field Progression in Open-Angle Glaucoma Eyes With Central Visual Field Damage
TL;DR: In this paper , the authors used OCT angiography to identify the baseline vessel density (VD) parameters that predict visual field (VF) progression in patients with open-angle glaucoma (OAG) with central visual fields (CVF) damage.
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Surgical management of coexisting cataract and glaucoma
Richard K. Lee,Steven J. Gedde +1 more
TL;DR: Evidence-based medicine with its comprehensive searches of the literature and analysis of data quality in clinical trials has led to conclusions regarding treatment outcomes and recommendations about glaucoma treatment and diagnosis.
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Detection of Early Glaucomatous Damage: Performance of Summary Statistics From Optical Coherence Tomography and Perimetry
TL;DR: OCT and VF metrics, single or in combinations, have only moderate sensitivity for eyes with early glaucoma and combinations evaluating S–S or S–F agreement can be highly specific, which is an important implication for clinical and research purposes.
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Agreement and Repeatability for Standard Automated Perimetry and Confocal Scanning Laser Ophthalmoscopy in the Diagnostic Innovations in Glaucoma Study
D. Ng,Linda M. Zangwill,Lyne Racette,Christopher Bowd,J.P. Pascual,Rupert R A Bourne,Catherine Boden,Robert N. Weinreb,Pamela A. Sample +8 more
TL;DR: The results suggest that detection of particular features of glaucomatous damage depends on the technique used and both structural and functional tests appear complementary, and both should be used for early detection ofglaucoma.
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Improving predictive models of glaucoma severity by incorporating quality indicators
TL;DR: Results showed that classification modelling is not negatively affected by the inclusion of less reliable tests in the training process, which could assist doctors in tuning patient follow-up and therapeutic plans, possibly slowing down disease progression.
9
References
Longitudinal data analysis using generalized linear models
Kung Yee Liang,Scott L. Zeger +1 more
TL;DR: In this article, an extension of generalized linear models to the analysis of longitudinal data is proposed, which gives consistent estimates of the regression parameters and of their variance under mild assumptions about the time dependence.
Proportional hazards tests and diagnostics based on weighted residuals
TL;DR: In this article, Chen et al. showed that a treatment effect that decreases with time can be directly visualized by smoothing an appropriate residual plot, which can be expressed as a weighted least-squares line fitted to the residual plot.
5.4K
Models for longitudinal data: a generalized estimating equation approach.
TL;DR: This article discusses extensions of generalized linear models for the analysis of longitudinal data in which heterogeneity in regression parameters is explicitly modelled and uses a generalized estimating equation approach to fit both classes of models for discrete and continuous outcomes.
The Lens Opacities Classification System III
Leo T. Chylack,John K. Wolfe,D.M. Singer,M. C. Leske,Mark A. Bullimore,Ian Bailey,Judith Friend,D. Mccarthy,Suh Yuh Wu +8 more
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Discrete sequential boundaries for clinical trials
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TL;DR: In this article, the authors proposed a more flexible method to construct discrete sequential boundaries based on the choice of a function, a*(t), which characterizes the rate at which the error level ac is spent.
2K