Dynamics of telomere length in captive Siamese cobra (Naja kaouthia) related to age and sex.
Worapong Singchat,Ekaphan Kraichak,Panupong Tawichasri,Tanapong Tawan,Aorarat Suntronpong,Siwapech Sillapaprayoon,Rattanin Phatcharakullawarawat,Narongrit Muangmai,Sunutcha Suntrarachun,Sudarath Baicharoen,Veerasak Punyapornwithaya,Surin Peyachoknagul,Lawan Chanhome,Kornsorn Srikulnath +13 more
TL;DR: An accelerated increase in telomere length of female cobra results from sex hormone stimulation to telomerase activity, reflecting sexually dimorphic phenotypic traits, and might also result from amplification of telomeric repeats on sex chromosomes.
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Abstract: Telomeres comprise tandem repeated DNA sequences that protect the ends of chromosomes from deterioration or fusion with neighboring chromosomes, and their lengths might vary with sex and age. Here, age- and sex-related telomere lengths in male and female captive Siamese cobras (Naja kaouthia) were investigated using quantitative real-time polymerase chain reaction based on cross-sectional data. A negative correlation was shown between telomere length and body size in males but not in females. Age-related sex differences were also recorded. Juvenile female snakes have shorter telomeres relative to males at up to 5 years of age, while body size also rapidly increases during this period. This suggests that an accelerated increase in telomere length of female cobra results from sex hormone stimulation to telomerase activity, reflecting sexually dimorphic phenotypic traits. This might also result from amplification of telomeric repeats on sex chromosomes. By contrast, female Siamese cobras older than 5 years had longer telomeres than males. Diverse sex hormone levels and oxidative stress parameters between sexes may affect telomere length.
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The evolution of aging
Leikola A
- 01 Jan 1966
TL;DR: The evolutionary theories of aging and longevity the aging of america the evolution of the aging population genetics and evolution of aging 1st edition fuclan atmospheric evolution and chemical aging of organic reverse evolution of Aging worldscientific aging, mating, and the Evolution of mtdna heteroplasmy in the evolutionof aging.
275
Decline in telomere length with increasing age across nonhuman vertebrates: A meta-analysis
Florentin Remot,Victor Ronget,Hannah Froy,Hannah Froy,Benjamin Rey,Jean-Michel Gaillard,Daniel H. Nussey,Jean-François Lemaître +7 more
TL;DR: The authors performed a meta-analysis to estimate the relationship between telomere length and age across 175 estimates encompassing 98 species of vertebrates and found that, on average, TL does decline with increasing age during adulthood.
54
Consequence of Paradigm Shift with Repeat Landscapes in Reptiles: Powerful Facilitators of Chromosomal Rearrangements for Diversity and Evolution.
Syed Farhan Ahmad,Worapong Singchat,Maryam Jehangir,Maryam Jehangir,Thitipong Panthum,Kornsorn Srikulnath +5 more
TL;DR: The exceptional karyotype variation and extreme genomic diversity of reptiles are used to test several hypotheses concerning genomic structure, function, and evolution.
33
Snake W Sex Chromosome: The Shadow of Ancestral Amniote Super-Sex Chromosome.
Worapong Singchat,Syed Farhan Ahmad,Nararat Laopichienpong,Aorarat Suntronpong,Thitipong Panthum,Darren K. Griffin,Kornsorn Srikulnath +6 more
TL;DR: The role of repeat-mediated sex chromosome conformation is highlighted and a genomic landscape of snake Z and W chromosomes is presented, which reveals the relative abundance of major repeats, and identifies the expansion of certain transposable elements.
19
Genome Complexity Reduction High-Throughput Genome Sequencing of Green Iguana (Iguana iguana) Reveal a Paradigm Shift in Understanding Sex-Chromosomal Linkages on Homomorphic X and Y Sex Chromosomes.
Tassika Koomgun,Nararat Laopichienpong,Worapong Singchat,Thitipong Panthum,Rattanin Phatcharakullawarawat,Ekaphan Kraichak,Siwapech Sillapaprayoon,Syed Farhan Ahmad,Narongrit Muangmai,Surin Peyachoknagul,Prateep Duengkae,Tariq Ezaz,Kornsorn Srikulnath +12 more
TL;DR: The results support the hypothesis of an ancestral super-sex chromosome with overlaps of partial sex-chromosomal linkages and provide an easy-to-use strategy for future research on the evolution of sex chromosomes in Iguanoidea, particularly for non-model species with homomorphic or highly cryptic sex chromosomes.
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