Dynamic Regional Brain Atrophy Rates in the First Year After Ischemic Stroke.
Amy Brodtmann,Mohamed Salah Khlif,Natalia Egorova,Natalia Egorova,Michele Veldsman,Laura Bird,Emilio Werden,Emilio Werden +7 more
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TL;DR: Regional atrophy rates vary over the first year after ischemic stroke, and rapid brain volume loss in the first 3 months after stroke may represent a potential window for intervention.
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Abstract: Background and Purpose: Brain atrophy can be regarded as an end-organ effect of cumulative cardiovascular risk factors. Accelerated brain atrophy is described following ischemic stroke, but it is n...
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More than motor impairment: A spatiotemporal analysis of cognitive impairment and associated neuropathological changes following cortical photothrombotic stroke:
Sonia Sanchez-Bezanilla,Rebecca J. Hood,Lyndsey E. Collins-Praino,Renée J. Turner,Frederick R. Walker,Michael Nilsson,Lin Kooi Ong +6 more
TL;DR: In this article, the authors investigated motor and cognitive impairments caused by a cortical stroke and found that a stroke can cause delayed and remote hippocampal dysregulation, leading to cognitive impairment.
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Blood Pressure and Vascular Cognitive Impairment
TL;DR: In this paper , a review of the epidemiology of high blood pressure and vascular cognitive impairment, including differences by sex, race, and ethnicity, is presented, as well as the management and reversibility of BP and VCI.
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Neurodegeneration Over 3 Years Following Ischaemic Stroke: Findings From the Cognition and Neocortical Volume After Stroke Study.
Amy Brodtmann,Emilio Werden,Mohamed Salah Khlif,Laura Bird,Natalia Egorova,Natalia Egorova,Michele Veldsman,Michele Veldsman,Heath R. Pardoe,Graeme D. Jackson,Graeme D. Jackson,Jennifer Bradshaw,David Darby,David Darby,Toby B Cumming,Leonid Churilov,Leonid Churilov,Geoffrey A. Donnan,Geoffrey A. Donnan +18 more
TL;DR: The CANVAS study as discussed by the authors found that stroke survivors who were cognitively normal at time of stroke had greater total brain (TBV) and hippocampal volume (HV) loss over 3 years than controls.
Investigating the microstructural properties of normal-appearing white matter (NAWM) preceding conversion to white matter hyperintensities (WMHs) in stroke survivors.
Wasim S. Khan,Wasim S. Khan,Mohamed Salah Khlif,Remika Mito,Thijs Dhollander,Amy Brodtmann,Amy Brodtmann +6 more
TL;DR: In this article, the microstructural properties of normal-appearing white matter (NAWM) preceding conversion to white matter hyperintensities (WMHs) were assessed using 3-tissue diffusion signal compositions in ischemic stroke.
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Causal effects of atrial fibrillation on brain white and gray matter volume: a Mendelian randomization study.
Sehoon Park,Soojin Lee,Soojin Lee,Soojin Lee,Yaerim Kim,Semin Cho,Semin Cho,Kwangsoo Kim,Yong Chul Kim,Seung Seok Han,Seung Seok Han,Hajeong Lee,Jung Pyo Lee,Jung Pyo Lee,So Ryoung Lee,So Ryoung Lee,Eue Keun Choi,Eue Keun Choi,Kwon Wook Joo,Kwon Wook Joo,Kwon Wook Joo,Chun Soo Lim,Chun Soo Lim,Yon Su Kim,Dong Ki Kim,Dong Ki Kim,Dong Ki Kim +26 more
TL;DR: In this paper, the causal effect of atrial fibrillation on brain volume phenotypes by Mendelian randomization (MR) analysis was assessed by two-sample MR by the inverse variance-weighted method supported by pleiotropy-robust MR sensitivity analysis.
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Neuroanatomical Correlates of Atrial Fibrillation: A Longitudinal MRI study
TL;DR: In this article, the authors analyzed clinical and neuroimaging data collected as part of Alzheimer's Disease Neuroimaging Initiative in the United States and Canada to determine baseline volume and rate of volume change of whole brain, hippocampus, and entorhinal cortex.
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