Journal Article10.1097/MD.0B013E3181E9441B
Drug-induced nephrotoxicity caused by amphotericin B lipid complex and liposomal amphotericin B: a review and meta-analysis.
Amar Safdar,Jonathan Ma,Fouzi Saliba,Bertrand Dupont,John R. Wingard,Ray Y Hachem,Gloria Mattiuzzi,Pranatharthi H. Chandrasekar,Dimitrios P. Kontoyiannis,Kenneth V. I. Rolston,Thomas J. Walsh,Richard E. Champlin,Issam I Raad +12 more
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TL;DR: The results suggest that nephrotoxicity is generally similar for ABLC and L-AmB in patients receiving antifungal therapy and prophylaxis in patients treating fungal infections.
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About: This article is published in Medicine. The article was published on 01 Jul 2010. The article focuses on the topics: Nephrotoxicity & Amphotericin B.
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Amphotericin B formulations: a comparative review of efficacy and toxicity.
TL;DR: The few comparative clinical trials that have been completed with the lipid-associated formulations have not demonstrated important clinical differences among these agents and amphotericin B for efficacy, although there are significant safety benefits of the lipid products.
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Thomas J. Walsh,Elias Anaissie,David W. Denning,Raoul Herbrecht,Dimitrios P. Kontoyiannis,Kieren A. Marr,Vicki A. Morrison,Vicki A. Morrison,Brahm H. Segal,William J. Steinbach,David A. Stevens,David A. Stevens,Jo Anne H. Van Burik,John R. Wingard,Thomas F. Patterson +14 more
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Kieren A. Marr,Rachel A. Carter,Fulvio Crippa,Anna Wald,Anna Wald,Lawrence Corey,Lawrence Corey +6 more
TL;DR: The results of the present study demonstrate the changing epidemiology of mould infections, emphasizing the increasing importance of amphotericin B--resistant organisms and the differences in risks and outcome of infection with different filamentous fungi.
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Rare and Emerging Opportunistic Fungal Pathogens: Concern for Resistance beyond Candida albicans and Aspergillus fumigatus
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Zygomycosis in a Tertiary-Care Cancer Center in the Era of Aspergillus-Active Antifungal Therapy: A Case-Control Observational Study of 27 Recent Cases
Dimitrios P. Kontoyiannis,Michail S. Lionakis,Russell E. Lewis,Russell E. Lewis,Georgios Chamilos,Mimi Healy,Cheryl Perego,Amar Safdar,Hagop M. Kantarjian,Richard E. Champlin,Thomas J. Walsh,Issam I Raad +11 more
TL;DR: Zygomycosis should be considered in immunosuppressed patients who develop sinusitis while receiving VRC prophylaxis, especially those with diabetes and malnutrition.
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