Patent
Dna sequence recognition
Andrei Rakitin,Andrey Ginovker,Alexander Dudelzak +2 more
- 19 Jan 2006
12
TL;DR: In this paper, a single strand of the probe DNA base sequence is linked to an electrode and the other end to a nano entity capable of exchanging charge with the DNA base sequences.
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Abstract: To detect the presence of a match of a target DNA base sequence with a probe DNA base sequence, a single strand of the probe DNA base sequence is prepared. One end of the single strand probe DNA base sequence is linked to an electrode and the other end to a nano entity capable of exchanging charge with the DNA base sequence. The single strand of the target DNA base sequence is brought into contact with the single strand of the probe DNA base sequence, and the change in the physical properties of the probe DNA base sequence upon hybridization detected.
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Citations
Regulation of cerebral cortical neurogenesis by the Pax6 transcription factor
TL;DR: The functional importance of Pax6 in regulating cortical progenitor proliferation, neurogenesis, and formation of cortical layers and highlight important differences between rodents and primates are reviewed and the pathological effects of PAX6 mutations in human neurodevelopmental disorders are reviewed.
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TL;DR: In this article, the authors describe a system for recognition of a translocating polymeric target molecule using a device having at least one constriction that is sized to permit translocation of only a single copy of the molecule.
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Stuart Lindsay,Jin He,Peiming Zhang +2 more
- 18 Mar 2009
TL;DR: In this article, the authors present a method for identifying strands of DNA as they pass through a constriction such as a carbon nanotube nanopore, which can be used to characterize that portion of the biopolymer.
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Colin Nuckolls,Jinyao Tang,Stuart Lindsay,Jin He,Peiming Zhang,Kevin Reinhart +5 more
- 18 Mar 2009
TL;DR: In this paper, a device for analyzing the composition of a heteropolymer comprising a carbon nanotube through which the heteropolymers is driven by electrophoresis is presented.
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Controlled tunnel gap device for sequencing polymers
Stuart Lindsay,Shuai Chang,Jin He,Peiming Zhang,Shuo Huang +4 more
- 31 Jan 2011
TL;DR: In this paper, the authors describe a method for analyzing a polymer and/or polymer unit using a transient bond between the reagent and the unit, which is generated and used to analyze the polymer.
40
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Patent
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TL;DR: In this paper, a method for detecting the presence of an analyte, such as a target nucleic acid sequence, protein sequence or small molecule, which can also be employed to detect the formation of duplex structures, is disclosed.
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Patent
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TL;DR: In this article, a highly sensitive method for electrochemically detecting a DNA using a novel mixed intercalator and a detection kit useful for practicing said method is described, which can be used for practice.
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