Journal Article10.1021/CR300340P
DNA-Mediated Homogeneous Binding Assays for Nucleic Acids and Proteins
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About: This article is published in Chemical Reviews. The article was published on 10 Apr 2013. The article focuses on the topics: Nucleic acid amplification technique & Nucleic acid thermodynamics.
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References
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
Craig Tuerk,Larry Gold +1 more
TL;DR: High-affinity nucleic acid ligands for a protein were isolated by a procedure that depends on alternate cycles of ligand selection from pools of variant sequences and amplification of the bound species.
10.4K
In vitro selection of RNA molecules that bind specific ligands.
TL;DR: Subpopulations of RNA molecules that bind specifically to a variety of organic dyes have been isolated from a population of random sequence RNA molecules.
9.7K
Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics
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TL;DR: The new generations of qdots have far-reaching potential for the study of intracellular processes at the single-molecule level, high-resolution cellular imaging, long-term in vivo observation of cell trafficking, tumor targeting, and diagnostics.
A DNA-based Method for Rationally Assembling Nanoparticles Into Macroscopic Materials
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6.6K
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