Book Chapter10.1007/978-3-030-85465-2_3
Discovery of Bioactive Natural Products from Bacillus Species: Chemistry, Biosynthesis and Biological Activities
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TL;DR: In this paper , the authors comprehensively review chemistry, biosynthetic pathways, and biological activities of natural products discovered in various strains of Bacillus spp., and discuss their application in biocontrol of plant diseases, medicines, and bioprospecting.
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Abstract: Bacillus is one of the most widely distributed genera of bacteria. It produces various groups of bioactive compounds such as cyclic lipopeptides, surfactins, iturins, fengycins, various polyketide-derived nonribosomal peptides, linear lipopeptides, enzymes, and δ-endotoxins with strong surfactant, antimicrobial, and insecticidal properties. Biosynthesis and chemistry of these bioactive natural products are largely been known. Genes involved in the biosynthesis of some of the bioactive compounds produced by Bacillus spp. are used in the genetic engineering of plants and microorganisms. Among them, genetically engineered Bt-crops significantly improved yield and quality of several crops. Recently developed CRISPR-Cas genome editing technology would facilitates the large-scale application of new genes of Bacillus involved in biosynthesis of bioactive compounds for promoting crop production and drug industry. This chapter comprehensively reviews chemistry, biosynthetic pathways, and biological activities of natural products discovered in various strains of Bacillus spp., and discusses their application in biocontrol of plant diseases, medicines, and bioprospecting.
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Citations
Suppressive Effects of Volatile Compounds from Bacillus spp. on Magnaporthe oryzae Triticum (MoT) Pathotype, Causal Agent of Wheat Blast
TL;DR: In this article , the antifungal effects of volatile organic compounds (VOCs) of Bacillus spp. were explored as a potential biocontrol mechanism against wheat blast.
Suppressive Effects of Volatile Compounds from <em>Bacillus </em>spp. on <em>Magnaporthe oryzae Triticum</em> (MoT) Pathotype, Causal Agent of Wheat Blast
18 Apr 2023
TL;DR: In this article , the antifungal effects of volatile organic compounds (VOCs) of Bacillus spp. were explored as a potential biocontrol mechanism against wheat blast.
4
Antimicrobial and anticancer potential of soil bacterial metabolites - a comprehensive and updated review
A Kumar,S. Kumaresan +1 more
TL;DR: Maheswari et al. as discussed by the authors reviewed phenolic compounds from Phaeophyceae as potential therapeutic agent and found that they are suitable for use in the treatment of cancer.
2
Isolation, structural characterization and sporicidal properties of Baelezcin A, a novel cyclic lipopeptide from Bacillus velezensis SJ100083 against gray mold.
Ziqiang Yuan,Boqing Zhou,Xiu-mi Wu,Li Wang,Guiling Li,Jingwen Liu,Qianjin Kang,Daren Wu,Jian Li +8 more
TL;DR: In this paper , Baelezcin A, extracted and purified from Bacillus velezensis SJ100083, was found effective in suppressing gray mold on cherries and was identified as a novel cyclic lipopeptide with molecular formula of C52 H91 N7 O13 through UHPLC-Q-Orbitrap HRMS.
Optimization of amylase and lipase enzymes produced by Bacillus cereus and Bacillus subtilis isolated from waste dumpsites
TL;DR: The study found that B. cereus and B. subtilis isolated from dumpsites could be efficient producers of biotechnology-relevant enzymes and that environmental conditions could influence their enzyme production.
References
Toxicity and Bioremediation of Heavy Metals Contaminated Ecosystem from Tannery Wastewater: A Review
Igiri Be,Stanley Irobekhian Reuben Okoduwa,Grace O. Idoko,Ebere P. Akabuogu,Abraham O. Adeyi,Ibe K. Ejiogu +5 more
TL;DR: The biosorption capacity with respect to the use of bacteria, fungi, biofilm, algae, genetically engineered microbes, and immobilized microbial cell for the removal of heavy metals is discussed.
Biocontrol of plant disease : a (Gram-) positive perspective
TL;DR: In this article, the authors describe several systems utilizing Gram-positive biocontrol agents that have been researched in depth and provide models for the future of biOControl.
687
Polyketide biosynthesis beyond the type I, II and III polyketide synthase paradigms.
TL;DR: Examples of polyketide synthases with much greater diversity in both mechanism and structure than the current type I, II and III paradigms serve as an inspiration for searching novel polyketid synthases to give new insights intopolyketide biosynthesis and to provide new opportunities for combinatorial biosynthesis.
543
Fengycin-a novel antifungal lipopeptide antibiotic produced by bacillus subtilis f-29-3
TL;DR: Fengycin is an antifungal lipopeptide complex produced by Bacillus subtilis strain F-29-3 that inhibits filamentous fungi but is ineffective against yeast and bacteria.
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Current models of the mode of action of Bacillus thuringiensis insecticidal crystal proteins: A critical review
TL;DR: It is concluded that the presently available information still supports the notion that Bt Cry toxins act by forming pores, but most events leading to their formation, following binding of the activated toxins to their receptors, remain relatively poorly understood.
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