Journal Article10.1038/35001029
Direct measurement of electrical transport through DNA molecules
1.7K
TL;DR: Measurements of electrical transport through individual 10.4-nm-long, double-stranded poly(G)-poly(C) DNA molecules connected to two metal nanoelectrodes that indicate, by contrast, large-bandgap semiconducting behaviour are presented.
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Abstract: Attempts to infer DNA electron transfer from fluorescence quenching measurements1,2,3,4,5,6,7,8,9 on DNA strands doped with donor and acceptor molecules have spurred intense debate10,11 over the question of whether or not this important biomolecule is able to conduct electrical charges. More recently, first electrical transport measurements on micrometre-long DNA ‘ropes’12, and also on large numbers of DNA molecules in films13, have indicated that DNA behaves as a good linear conductor. Here we present measurements of electrical transport through individual 10.4-nm-long, double-stranded poly(G)-poly(C) DNA molecules connected to two metal nanoelectrodes, that indicate, by contrast, large-bandgap semiconducting behaviour. We obtain nonlinear current–voltage curves that exhibit a voltage gap at low applied bias. This is observed in air as well as in vacuum down to cryogenic temperatures. The voltage dependence of the differential conductance exhibits a peak structure, which is suggestive of the charge carrier transport being mediated by the molecular energy bands of DNA.
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Electrical conduction through DNA molecules
TL;DR: Direct measurements of electrical current as a function of the potential applied across a few DNA molecules associated into single ropes at least 600 nm long indicate that DNA transports electricalCurrent as efficiently as a good semiconductor.
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Charge transfer and transport in DNA
TL;DR: The energetic-dynamic relations, in conjunction with the energetic data for d*/d- and for B/B+, determine the realization of the two distinct mechanisms in different hole donor systems, establishing the conditions for "chemistry at a distance" after charge transport in DNA.
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