Book Chapter10.1007/978-3-540-78576-7_14
Diffusion-Weighted Whole-Body Imaging with Background Body Signal Suppression (DWIBS)
Taro Takahara,Thomas C. Kwee +1 more
- 01 Jan 2010
- pp 227-252
698
TL;DR: Three-dimensional DWIBS can be obtained with this technique, which may allow us to screen for malignancies in the whole body through diffusion weighted whole body imaging with background body signal suppression.
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Abstract: In applying diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) technique, DW-MR images are acquired during free breathing, which results in images with high signal-to-noise ratio using relatively thin image sections (4–5 mm). Image acquisition during free breathing is possible because bulk tissue motion, including respiratory motion, may be considered as types of coherent motion, which do not result in significant signal loss unlike intravoxel incoherent motion, which reflects random water motion at a cellular level. The concept of DWIBS allows handling of the acquired images as a volumetric dataset and it exploits both prolonged T2 relaxation time and impeded diffusion that the majority of solid lesions (both benign and malignant) exhibit as mechanisms for image contrast, which is used for clinical evaluation of diseases.
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Citations
Benign and malignant enlarged chest nodes staging by diffusion-weighted MRI: an alternative to mediastinoscopy?
Monica Sigovan,Pia Akl,Caroline Mesmann,François Tronc,Salim Si-Mohamed,Salim Si-Mohamed,Philippe Douek,Philippe Douek,Loic Boussel,Loic Boussel +9 more
TL;DR: MRI DWIBS can accurately differentiate malignant from benign states in enlarged mediastinal lymph-nodes and represents an alternative method in aetiological work-up of mediastsinal lymphadenopathies and may reduce the frequency of futile mediastinoscopy, which remains an invasive procedure.
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Visualizing whole-body treatment response heterogeneity using multi-parametric magnetic resonance imaging:
Matthew D. Blackledge,Mihaela Rata,Nina Tunariu,Dow-Mu Koh,Angela George,Andrea Zivi,Andrea Zivi,David Lorente,Gerhardt Attard,Johann S. de Bono,Martin O. Leach,David J. Collins +11 more
TL;DR: A novel post-processing methodology able to assess whole-body tumor heterogeneity in patients with metastatic disease is proposed and provides spatially heterogeneous characterization of regions following treatment as defined by the combined analysis of apparent diffusion coefficient and fractional enhancement.
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Evaluation of image quality of DWIBS versus DWI sequences in thoracic MRI at 3T.
Caroline Mesmann,Monica Sigovan,Lise-Prune Berner,Adva Abergel,François Tronc,Yves Berthezène,Philippe Douek,Loic Boussel +7 more
TL;DR: In thoracic MRI, ungated DWIBS sequence improves fat-sat homogeneity, reduces motion artifacts and increases STB of lymph nodes.
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se Positron Emission Tomography/ Magnetic Resonance Imaging Current Status, Future Aspects
Rajan Rakheja,Hersh Chandarana,Fabio Ponzo,Alexandra Seltzer,Luis S. Beltran,Christian Geppert,Kent Friedman +6 more
- 01 Jan 2014
TL;DR: In this paper, the authors proposed a total imaging time of approximately 45 to 70 minutes with simultaneous PET/magnetic resonance (MRI) imaging, making this a feasible total body imaging protocol.
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Characterization of head and neck lesions with diffusion-weighted MR imaging and the apparent diffusion coefficient values
TL;DR: DWI and the ADC measurement are promising, non-invasive imaging approach that can be used for characterization of head and neck lesions and can help differentiate malignant tumors from benign lesions.
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Diffusion-weighted MRI in the body: applications and challenges in oncology.
Dow-Mu Koh,David J. Collins +1 more
TL;DR: The basic principles of diffusion-weighted imaging (DWI) are presented that can aid radiologists in the qualitative and quantitative interpretation of DW images and provide unique insights about tumor cellularity and the integrity of cell membranes.
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TL;DR: Because stroke is common and in the differential diagnosis of most acute neurologic events, diffusion-weighted MR imaging should be considered an essential sequence, and its use in most brain MR studies is recommended.
Clinical Applications of PET in Oncology
TL;DR: The physics and instrumentation aspects of PET, an analogue of glucose, are described and are being used in diagnosis and follow-up of several malignancies, and the list of articles supporting its use continues to grow.
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•Journal Article
Diffusion weighted whole body imaging with background body signal suppression (DWIBS): technical improvement using free breathing, STIR and high resolution 3D display.
TL;DR: In this article, the authors examined a new way of body diffusion weighted imaging (DWI) using the short TI inversion recovery-echo planar imaging (STIR-EPI) sequence and free breathing scanning (diffusion weighted whole body imaging with background body signal suppression; DWIBS) to obtain three-dimensional displays.
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