Journal Article10.1016/J.EJCA.2005.07.023
Differential sensitivity of liposarcoma subtypes to chemotherapy.
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TL;DR: A retrospective analysis of a prospectively maintained database of soft tissue sarcoma patients treated at the Royal Marsden Hospital suggests that myxoid liposarcoma is relatively chemosensitive in comparison to a combination of other liposARcomas, and in particular de- and well-differentiated tumours.
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About: This article is published in European Journal of Cancer. The article was published on 01 Dec 2005. The article focuses on the topics: Myxoid liposarcoma & Liposarcoma.
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Citations
The intriguing patterns of tumor response to trabectedin.
TL;DR: The finding of trabectedin’s ability to target the FUS-CHOP-mediated transcriptional block, restoring adipogenic differentiation within the tumor in myxoid liposarcomas, confirmed a ‘targeted’ activity that differs from its well-known atypical alkylating mechanism of action.
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Surgical resection of a well-differentiated inflammatory liposarcoma of the middle mediastinum: a case report.
Makoto Edagawa,Naoki Haratake,Shinichiro Shimamatsu,Ryo Toyozawa,Kaname Nosaki,Fumihiko Hirai,Masafumi Yamaguchi,Kenichi Taguchi,Koichiro Kaneko,Takashi Seto,Mitsuhiro Takenoyama,Yukito Ichinose +11 more
TL;DR: The first report of a well-differentiated inflammatory liposarcoma arising from the middle mediastinum arising from a 68-year-old woman is experienced, to the best of the authors' knowledge.
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Dedifferentiated liposarcoma in the extremity and trunk wall: A multi-institutional study of 132 cases by the Japanese Musculoskeletal Oncology Group (JMOG).
Takeshi Morii,Ukei Anazawa,Chiaki Sato,Shintaro Iwata,Makoto Nakagawa,Makoto Ando,Tomoki Nakamura,Kunihiro Ikuta,Yoshihiro Nishida,Robert Nakayama,Toru Udaka,Teruya Kawamoto,Munehisa Kito,Kenji Sato,Jungo Imanishi,Toru Akiyama,Hiroshi Kobayashi,Akihito Nagano,Hidetatsu Outani,Shunichi Toki,Toshihiko Nishisho,Keita Sasa,Yoshiyuki Suehara,Hirotaka Kawano,Takafumi Ueda,Hideo Morioka +25 more
TL;DR: In this paper , the authors analyzed the clinical characteristics of dedifferentiated liposarcoma in the extremities and trunk wall in a retrospective, multicentric study with 132 patients and found that the mean duration from the initial presentation to dedifferentiation was 101 months.
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TL;DR: A second multivariate analysis introducing clinical prognostic features showed that the histological grade was the most important prognostic factor for soft‐tissue sarcomas and appears to be highly interesting because of its prognostic value and the facility of its elaboration.
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Comparative study of the National Cancer Institute and French Federation of Cancer Centers Sarcoma Group grading systems in a population of 410 adult patients with soft tissue sarcoma
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TL;DR: The FNCLCC system showed slightly increased ability to predict distant metastasis development and tumor mortality, and the use of this system to evaluate STS aggressiveness might be favored.
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Gemcitabine and Docetaxel in Patients With Unresectable Leiomyosarcoma: Results of a Phase II Trial
Martee L. Hensley,Robert G. Maki,Ennapadam Venkatraman,Gennifer Geller,Meghan Lovegren,Carol Aghajanian,Paul Sabbatini,William P. Tong,Richard Barakat,David R. Spriggs +9 more
TL;DR: Gemcitabine plus docetaxel is tolerable and highly active in treated and untreated patients with LMS, and Hematologic toxicity was common, but neutropenic fever and bleeding events were rare.
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