Differences in ATP Generation Via Glycolysis and Oxidative Phosphorylation and Relationships with Sperm Motility in Mouse Species
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TL;DR: It is found that the sperm of species with higher oxygen consumption/lactate excretion rate ratios were able to produce higher amounts of ATP, achieving higher swimming velocities and that sexual selection could promote adaptations in sperm energetic metabolism tending to increase the usage of a more efficient pathway for the generation of ATP.
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About: This article is published in Journal of Biological Chemistry. The article was published on 14 Aug 2015. and is currently open access. The article focuses on the topics: Sperm motility & Anaerobic glycolysis.
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Citations
Capacitation increases glucose consumption in murine sperm.
David Martin Hidalgo,David Martin Hidalgo,Ana Romarowski,Maria Gracia Gervasi,Felipe Navarrete,Melanie Balbach,Ana M. Salicioni,Lonny R. Levin,Jochen Buck,Pablo E. Visconti +9 more
TL;DR: It is shown that glucose consumption is enhanced in media that support mouse sperm capacitation suggesting upregulation of glucose metabolic pathways and cAMP and calcium pathways are involved in the regulation of glycolytic energy pathways during murine sperm capacitate.
miR-26a is Involved in Glycometabolism and Affects Boar Sperm Viability by Targeting PDHX
Wencan Wang,Kai Liang,Yu Chang,Ming-Xia Ran,Yan Zhang,Malik Ahsan Ali,Dinghui Dai,Izhar Hyder Qazi,Izhar Hyder Qazi,Ming Zhang,Guang-Bin Zhou,Jiandong Yang,Christiana Angel,Changjun Zeng +13 more
TL;DR: The novel and enticing findings of this study provide a reasonable evidence that miR-26a via PDHX, a link between glycolysis and oxidative phosphorylation, could regulate the glycometabolic pathway which eventually affect boar sperm viability and survival.
Functions and effects of reactive oxygen species in male fertility.
TL;DR: This review paper will focus on describing the predominant sources of ROS in the ejaculate, the effects of ROS on a cellular and molecular level, and the actions of ROS from the whole animal perspective.
Sperm competition and the evolution of sperm form and function in mammals.
TL;DR: A more thorough understanding of the diversity in structure and function of sperm cells, and underlying selective forces, may help to develop better methods to assess them and become more reliable in estimations of the impact of cryopreservation or effect of changes in the environment and their relevance for fertility.
Productivity and fresh semen characteristics of simmental bull different ages
Faisal Amri Satrio,Ni Wayan Kurniani Karja,Mohamad Agus Setiadi,Ekayanti Mulyawati Kaiin,Asep Saepul Kurnia,Bambang Purwantara +5 more
TL;DR: In this paper , the effect of age on the productivity and fresh semen characteristics of Simmental bull in Indonesia was investigated. And the results showed that the prefreezing and post-freezing semen rejection rate of ≥ 10 HR group was higher (P0.05) than other groups.
References
Sperm competition and its evolutionary consequences in the insects
TL;DR: In this article, Simpson et al. describe a method to solve the problem of homonymity in Bee W l d 34, 14) and show that it works well in beekeeping.
4.1K
Premature ageing in mice expressing defective mitochondrial DNA polymerase
Aleksandra Trifunovic,Anna Wredenberg,Maria Falkenberg,Johannes N. Spelbrink,Anja T. Rovio,Carl E.G. Bruder,Mohammad Bohlooly-Y,Sebastian Gidlöf,Anders Oldfors,Rolf Wibom,Jan Törnell,Howard T. Jacobs,Nils-Göran Larsson +12 more
TL;DR: The results provide a causative link between mtDNA mutations and ageing phenotypes in mammals by creating homozygous knock-in mice that express a proof-reading-deficient version of PolgA, the nucleus-encoded catalytic subunit of mtDNA polymerase.
2.7K
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TL;DR: The critical role of glycolysis in sperm and its dependence on this sperm-specific enzyme suggest that GAPDS is a potential contraceptive target, and that mutations or environmental agents that disrupt its activity could lead to male infertility.
620
Mitochondria functionality and sperm quality
TL;DR: The aim of this review was to discuss the putative roles of mitochondria in mammalian sperm function and how they may relate to sperm quality and fertilisation ability, particularly in humans.
Glycolysis Plays a Major Role for Adenosine Triphosphate Supplementation in Mouse Sperm Flagellar Movement
Chinatsu Mukai,Makoto Okuno +1 more
TL;DR: The present results suggest that glycolysis has an unexpectedly important role in providing the ATP required for sperm motility throughout the length of the sperm flagellum.
447