Differences in ATP Generation Via Glycolysis and Oxidative Phosphorylation and Relationships with Sperm Motility in Mouse Species
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TL;DR: It is found that the sperm of species with higher oxygen consumption/lactate excretion rate ratios were able to produce higher amounts of ATP, achieving higher swimming velocities and that sexual selection could promote adaptations in sperm energetic metabolism tending to increase the usage of a more efficient pathway for the generation of ATP.
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About: This article is published in Journal of Biological Chemistry. The article was published on 14 Aug 2015. and is currently open access. The article focuses on the topics: Sperm motility & Anaerobic glycolysis.
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Citations
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TL;DR: Future workers on dog spermatozoa should bear in mind major differences between breeds and realize that results cannot be extrapolated from one to another, as dogs may represent a good model to examine changes in reproductive parameters associated with selection processes.
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Ortho‐phenylphenol exposure impairs porcine sperm motility through AMPK/AKT signaling pathway
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Hwang I.S. Thomas,Hwang I.S. Thomas,Hwang I.S. Thomas,Ying Shiuan Chen,Ching Han Hung,Dilip Bhargava Sreerangaraja Urs,Tien Ling Liao,Yen Chun Lai,Katerina Komrskova,Katerina Komrskova,Pavla Postlerova,Pavla Postlerova,Yung Feng Lin,Shu Huei Kao,Shu Huei Kao +14 more
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References
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Premature ageing in mice expressing defective mitochondrial DNA polymerase
Aleksandra Trifunovic,Anna Wredenberg,Maria Falkenberg,Johannes N. Spelbrink,Anja T. Rovio,Carl E.G. Bruder,Mohammad Bohlooly-Y,Sebastian Gidlöf,Anders Oldfors,Rolf Wibom,Jan Törnell,Howard T. Jacobs,Nils-Göran Larsson +12 more
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TL;DR: The critical role of glycolysis in sperm and its dependence on this sperm-specific enzyme suggest that GAPDS is a potential contraceptive target, and that mutations or environmental agents that disrupt its activity could lead to male infertility.
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TL;DR: The aim of this review was to discuss the putative roles of mitochondria in mammalian sperm function and how they may relate to sperm quality and fertilisation ability, particularly in humans.
Glycolysis Plays a Major Role for Adenosine Triphosphate Supplementation in Mouse Sperm Flagellar Movement
Chinatsu Mukai,Makoto Okuno +1 more
TL;DR: The present results suggest that glycolysis has an unexpectedly important role in providing the ATP required for sperm motility throughout the length of the sperm flagellum.
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