Diagnostics
Ronald M. Razmi
- 05 Jan 2024
pp 113-155
TL;DR: Diagnostics involve radiology, pathology, dermatology, ophthalmology, and cardiology. Images and visual inspections are key to diagnosis in these specialties.
read more
Abstract: Radiology is the first area for the reader to look at because images are digital files with structured data that can be used to develop and validate models to perform a narrow task such as finding a tumor on a CT scan or a fracture on an X-ray. The field of pathology is critical to both the diagnosis and treatment of many cancers, yet the tools of the trade haven't been upgraded much in 100 years. Consistent with radiology and pathology, dermatology is another specialty where a lot of the diagnosis comes down to a visual inspection of the skin and doing pattern recognition. Ophthalmology is another specialty where the examination of the eye is a huge part of screening and diagnosis. In cardiology, most diseases are slow, multi-morbid, heterogeneous, and chronic, with pathogenesis beginning decades before the disease actually manifests.
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
References
Dermatologist-level classification of skin cancer with deep neural networks
Andre Esteva,Brett Kuprel,Roberto A. Novoa,Justin M. Ko,Susan M. Swetter,Susan M. Swetter,Helen M. Blau,Sebastian Thrun +7 more
TL;DR: This work demonstrates an artificial intelligence capable of classifying skin cancer with a level of competence comparable to dermatologists, trained end-to-end from images directly, using only pixels and disease labels as inputs.
11.8K
Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs
Varun Gulshan,Lily Peng,Marc Coram,Martin C. Stumpe,Derek Wu,Arunachalam Narayanaswamy,Subhashini Venugopalan,Kasumi Widner,Tom Madams,Jorge Cuadros,Ramasamy Kim,Rajiv Raman,Philip C. Nelson,Jessica L. Mega,Dale R. Webster +14 more
TL;DR: An algorithm based on deep machine learning had high sensitivity and specificity for detecting referable diabetic retinopathy and diabetic macular edema in retinal fundus photographs from adults with diabetes.
Diagnostic Assessment of Deep Learning Algorithms for Detection of Lymph Node Metastases in Women With Breast Cancer.
Babak Ehteshami Bejnordi,Mitko Veta,Paul J. van Diest,Bram van Ginneken,Nico Karssemeijer,Geert Litjens,Jeroen van der Laak,Meyke Hermsen,Quirine F. Manson,Maschenka Balkenhol,Oscar Geessink,N. Stathonikos,Marcory C. R. F. van Dijk,Peter Bult,Francisco Beca,Andrew H. Beck,Dayong Wang,Aditya Khosla,Rishab Gargeya,Humayun Irshad,Aoxiao Zhong,Qi Dou,Qi Dou,Quanzheng Li,Hao Chen,Huangjing Lin,Pheng-Ann Heng,Christian Haß,Elia Bruni,Quincy Wong,Ugur Halici,Mustafa Umit Oner,Rengul Cetin-Atalay,Matt Berseth,Vitali Khvatkov,Alexei Vylegzhanin,Oren Kraus,Muhammad Shaban,Nasir M. Rajpoot,Nasir M. Rajpoot,Ruqayya Awan,Korsuk Sirinukunwattana,Talha Qaiser,Yee-Wah Tsang,David Tellez,Jonas Annuscheit,Peter Hufnagl,Mira Valkonen,Kimmo Kartasalo,Kimmo Kartasalo,Leena Latonen,Pekka Ruusuvuori,Pekka Ruusuvuori,Kaisa Liimatainen,Shadi Albarqouni,Bharti Mungal,Ami George,Stefanie Demirci,Nassir Navab,Seiryo Watanabe,Shigeto Seno,Yoichi Takenaka,Hideo Matsuda,Hady Ahmady Phoulady,Vassili Kovalev,A. Kalinovsky,Vitali Liauchuk,Gloria Bueno,M. Milagro Fernández-Carrobles,Ismael Serrano,Oscar Deniz,Daniel Racoceanu,Daniel Racoceanu,Rui Venâncio +73 more
TL;DR: In the setting of a challenge competition, some deep learning algorithms achieved better diagnostic performance than a panel of 11 pathologists participating in a simulation exercise designed to mimic routine pathology workflow; algorithm performance was comparable with an expert pathologist interpreting whole-slide images without time constraints.
Prediction of cardiovascular risk factors from retinal fundus photographs via deep learning
Ryan Poplin,Avinash V. Varadarajan,Katy Blumer,Yun Liu,Michael V. McConnell,Greg S. Corrado,Lily Peng,Dale R. Webster +7 more
TL;DR: In this article, the authors used deep learning models trained on retinal fundus images to predict cardiovascular risk factors not previously thought to be present or quantifiable in retinal images.
1.4K
Pivotal trial of an autonomous AI-based diagnostic system for detection of diabetic retinopathy in primary care offices
Michael D. Abràmoff,Philip T. Lavin,Michele Birch,Nilay Shah,James C. Folk,James C. Folk +5 more
- 28 Aug 2018
TL;DR: FDA authorized the system for use by health care providers to detect more than mild DR and diabetic macular edema, making it, the first FDA authorized autonomous AI diagnostic system in any field of medicine, with the potential to help prevent vision loss in thousands of people with diabetes annually.