Journal Article10.1146/ANNUREV.EN.41.010196.001203
Development of Recombinant Baculoviruses for Insect Control
TL;DR: The development of genetically engineered baculoviruses for use as rapid-action biological insecticides, and more detailed information on one particular set of recombinant viruses are provided.
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Abstract: In this review, we provide an overview of the current status of recombinant baculoviruses, describe the development of genetically engineered baculoviruses for use as rapid-action biological insecticides, and provide more detailed information on one particular set of recombinant viruses. The advantages and disadvantages of recombinant baculovirus insecticides, and the importance of risk-assessment studies of these genetically modified organisms, are reviewed. Finally the importance of sensible regulatory strategies to the success and future prospects of this technology is discussed.
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Citations
Effect of Deltamethrin Treatment on Lepidopteran Larvae Infected with Baculoviruses Expressing Insect-Selective Toxins μ-Aga-IV, As II, or Sh 1☆
Holly J.R. Popham,Grigori G. Prikhod'ko,Thomas J. Felcetto,Dan A. Ostlind,Jeffrey W. Warmke,Charles J. Cohen,Lois K. Miller +6 more
TL;DR: The results indicate that coapplication of this pyrethroid will confer little or no advantage in field applications of recombinant baculovirus pesticides and that application of pyrethroids will probably have no adverse affect on recombinant virus efficacy unless it deters larval feeding and virus acquisition.
A novel recombinant baculovirus overexpressing a Bacillus thuringiensis Cry1Ab toxin enhances insecticidal activity.
TL;DR: A truncated form of cry1Ab gene derived from Bacillus thuringinsis (Bt) subsp.
A new, rapid and simple procedure for direct cloning of PCR products into baculoviruses
TL;DR: The direct cloning of green fluorescent protein and beta-glucuronidase in different baculovirus loci is described and the method is simple and avoids the use of cumbersome techniques associated with enzymatic treatment and DNA purification.
AaIT: From neurotoxin to insecticide
TL;DR: The AaIT is a pharmacological tool for the study of insect neuronal excitability and chemical ecology and the development of new approaches to insect control.
Baculovirus‐mediated expression of a scorpion depressant toxin improves the insecticidal efficacy achieved with excitatory toxins
TL;DR: The higher insecticidity of the virus expressing the depressant toxin compared to the excitatory toxin suggests that pharmacokinetic factors and/or promoter efficiency may play a role during infection of insect pest larvae by recombinant baculoviruses.
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