Development of artemether-loaded nanostructured lipid carrier (NLC) formulation for topical application

TL;DR: The importance of the implementation of prepared nanomaterials loaded with bioactive compounds from herb extracts into real food and novel technologies that offer new capabilities like nanotubes or nanofibers may because of their high surface to volume ratio allow achieving desirable actions.

TL;DR: In this paper, the authors describe enhanced bioavailability of paliperidone palmitate through transdermal delivery using nanostructured lipid carriers (NLCs) formulated by nanoparticles.

TL;DR: Evaluation of emulgel and nanostructured lipid carrier-based gel formulations for transdermal administration of ibuprofen: Characterization, mechanical properties, and ex-vivo skin permeation. The study evaluated the rheological and mechanical properties of various formulations and found E2 formulation to be the most suitable for transdermal application due to its high viscosity, firmness, and increased skin permeation.

TL;DR: In this article , the authors evaluated the antimalarial efficacy of artemether-loaded polymeric nanorods for the treatment of severe malaria by the intramuscular route.

TL;DR: NTA is a powerful characterization technique that complements DLS and is particularly valuable for analyzing polydisperse nanosized particles and protein aggregates.

TL;DR: The findings show that the malaria mortality burden is larger than previously estimated, especially in adults, and there has been a rapid decrease in malaria mortality in Africa because of the scaling up of control activities supported by international donors.

TL;DR: Evidence of the clinical implications and burden of malaria in pregnancy is reviewed and Meta-analyses of intervention trials suggest that successful prevention of P falciparum infections during pregnancy reduces the risk of severe maternal anaemia, low birthweight, and perinatal mortality among paucigravidae.

TL;DR: In this article, the authors reviewed evidence of the clinical implications and burden of malaria in pregnancy and found that successful prevention of these infections reduces the risk of severe maternal anaemia by 38%, low birthweight by 43%, and perinatal mortality by 27% among paucigravidae.