Development of a Peptide Reactivity Assay for Screening Contact Allergens
G. Frank Gerberick,Jeffrey D. Vassallo,Ruth E. Bailey,Joel G. Chaney,Morrall Stephen William,Jean-Pierre Lepoittevin +5 more
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TL;DR: The data presented show that measuring peptide reactivity has utility for screening chemicals for their skin sensitization potency and thus potential for reducing the authors' reliance on animal test methods.
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About: This article is published in Toxicological Sciences. The article was published on 01 Oct 2004. and is currently open access. The article focuses on the topics: Sensitization & Local lymph node assay.
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Validation of Quantitative Structure-Activity Relationship (QSAR) and Quantitative Structure-Property Relationship (QSPR) approaches as alternatives to skin sensitization risk assessment
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