Journal Article10.1016/J.EJPB.2006.10.014
Development and bioavailability assessment of ramipril nanoemulsion formulation.
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TL;DR: The present study revealed that ramipril nanoemulsion could be used as a liquid formulation for pediatric and geriatric patients and can be formulated as self-nanoemulsifying drug delivery system (SNEDDS) as a unit dosage form.
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About: This article is published in European Journal of Pharmaceutics and Biopharmaceutics. The article was published on 01 May 2007. The article focuses on the topics: Dosage form.
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Citations
Preparation and Evaluation of a Self-Emulsifying Drug Delivery System for Improving the Solubility and Permeability of Ticagrelor
Anam Aziz,Muhammad Zaman,M. A. Khan,Talha Jamshaid,Muhammad Hammad Butt,Huma Hameed,Muhammad Shafeeq Ur Rahman,Qurat-ul-ain Shoaib +7 more
TL;DR: The development and evaluation of a self-emulsifying drug delivery system (SNEDDS) for improving the solubility and permeability of ticagrelor (TCG) is described. The SNEDDS formulations exhibited improved dissolution and permeation of TCG, leading to enhanced antiplatelet activity.
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Self-Emulsified Nanoemulsion for Vaginal Administration: In Vitro Study of Effect on Lactobacillus acidophilus.
TL;DR: Self-emulsified nanoemulsions (SENs), one of the promising lipid-based drug delivery systems may be used to deliver drugs through vaginal route, showed inhibitory effects on the growth of L. acidophilus in a concentration-dependent manner.
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Formulation Development and Bioavailability Assessment of Aripiprazole by Self-Nanoemulsifying Drug Delivery Systems
TL;DR: SNEDDS can be effective oral dosage form for enhancing aqueous solubility and thereby improving oral BA of poorly water-soluble drug, APZ.
•Journal Article
Self Emulsifying Drug Delivery System: A Gentle Approach for drug delivery
TL;DR: Self-emulsifying drug delivery system is one the most important and advanced technology for enhancing the oral bio-availability as well reducing in dose for enabling more consistent drug absorption, selective targeting of drugs in GIT, and protection of drugs from the inner environment of gut.
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Pharmaceutical Emulsions: A Viable Approach for Ocular Drug Delivery.
Amol Chhatrapati Bisen,Saurabh Srivastava,Anjali Mishra,Sachin Nashik Sanap,Arpon Biswas,Abhijit Deb Choudhury,Ayush Dubey,Neeraj Mohan Gupta,Karan Yadav,Madhav Nilakanth Mugale,Rabi Sankar Bhatta +10 more
TL;DR: This review presents, in brief, recent emulsion-based patented innovations, clinical trials, and marketed emulsion formulations for ocular drug delivery, which are strengthening development of the new ophthalmic drug products for managing different ocular diseases and disorders.
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Effects of an angiotensin-converting -enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients
TL;DR: Ramipril significantly reduces the rates of death, myocardial infarction, and stroke in a broad range of high-risk patients who are not known to have a low ejection fraction or heart failure.
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A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability
TL;DR: A biopharmaceutics drug classification scheme for correlating in vitro drug product dissolution and in vivo bioavailability is proposed based on recognizing that drug dissolution and gastrointestinal permeability are the fundamental parameters controlling rate and extent of drug absorption.
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Encyclopedia of Pharmaceutical Technology
James Swarbrick
- 01 Oct 2006
TL;DR: Compounding, Contemporary, andProcess Chemistry in the Pharmaceutical Industry: Characterization and Function, Volume 19.
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Microemulsion-based media as novel drug delivery systems
M. Jayne Lawrence,Gareth D. Rees +1 more
TL;DR: The use of microemulsions and closely related microemulsion-based systems as drug delivery vehicles is reviewed, with particular emphasis being placed on recent developments and future directions.
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Nano-emulsion formulation using spontaneous emulsification: solvent, oil and surfactant optimisation
TL;DR: This phase of emulsion optimisation represents an important step in the process of polymeric nanocapsules preparation using nanoprecipitation or interfacial polycondensation combined with spontaneous emulsification technique.
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