Journal Article10.1016/J.EJPB.2006.10.014
Development and bioavailability assessment of ramipril nanoemulsion formulation.
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TL;DR: The present study revealed that ramipril nanoemulsion could be used as a liquid formulation for pediatric and geriatric patients and can be formulated as self-nanoemulsifying drug delivery system (SNEDDS) as a unit dosage form.
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About: This article is published in European Journal of Pharmaceutics and Biopharmaceutics. The article was published on 01 May 2007. The article focuses on the topics: Dosage form.
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Citations
Development of loteprednol etabonate-loaded cationic nanoemulsified in-situ ophthalmic gel for sustained delivery and enhanced ocular bioavailability.
TL;DR: A novel cationic nanoemulsified in-situ ophthalmic gel of loteprednol etabonate (LE) was developed to improve the permeability and retention time of formulations for overall improvement of drug’s ocular bioavability.
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Chaulmoogra oil based methotrexate loaded topical nanoemulsion for the treatment of psoriasis
TL;DR: Chaulmoogra oil based methotrexate loaded nanoemulsion was prepared via emulsification technique using tween 80 and ethanol as surfactants in this paper, the formulation was characterized by FTIR and TEM.
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Critical steps and energetics involved in a successful development of a stable nanoemulsion
TL;DR: This review clarifies the concepts found in the literature regarding NE development, components screening, preparation techniques, evaluation parameters and stability issues with respect to the significance of pseudo-ternary phase diagrams and framed about the critical steps involved in the development of stable NEs.
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Nanoemulsion: A Novel Drug Delivery Approach for Enhancement of Bioavailability.
TL;DR: Nanoemulsion can be developed in many dosage forms such as oral, parenteral, topical, ophthalmic dosage form in large scale using common operation at a very low cost.
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Development of Novel Ionic Liquid-Based Microemulsion Formulation for Dermal Delivery of 5-Fluorouracil
TL;DR: The results of in vivo studies against dimethylbenz(a)anthracene/12-O-tetradecanoylphorbol-13-acetate-induced mice skin carcinogenesis demonstrated that the IL/o ME could effectively treat skin cancer in 4 weeks and suggest that the use of IL-based ME system can efficiently enhance the solubility and permeability of 5-FU and hence its therapeutic efficacy.
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References
Effects of an angiotensin-converting -enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients
TL;DR: Ramipril significantly reduces the rates of death, myocardial infarction, and stroke in a broad range of high-risk patients who are not known to have a low ejection fraction or heart failure.
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A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability
TL;DR: A biopharmaceutics drug classification scheme for correlating in vitro drug product dissolution and in vivo bioavailability is proposed based on recognizing that drug dissolution and gastrointestinal permeability are the fundamental parameters controlling rate and extent of drug absorption.
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Encyclopedia of Pharmaceutical Technology
James Swarbrick
- 01 Oct 2006
TL;DR: Compounding, Contemporary, andProcess Chemistry in the Pharmaceutical Industry: Characterization and Function, Volume 19.
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Microemulsion-based media as novel drug delivery systems
M. Jayne Lawrence,Gareth D. Rees +1 more
TL;DR: The use of microemulsions and closely related microemulsion-based systems as drug delivery vehicles is reviewed, with particular emphasis being placed on recent developments and future directions.
1.9K
Nano-emulsion formulation using spontaneous emulsification: solvent, oil and surfactant optimisation
TL;DR: This phase of emulsion optimisation represents an important step in the process of polymeric nanocapsules preparation using nanoprecipitation or interfacial polycondensation combined with spontaneous emulsification technique.
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