Journal Article10.1016/J.EJPB.2006.10.014
Development and bioavailability assessment of ramipril nanoemulsion formulation.
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TL;DR: The present study revealed that ramipril nanoemulsion could be used as a liquid formulation for pediatric and geriatric patients and can be formulated as self-nanoemulsifying drug delivery system (SNEDDS) as a unit dosage form.
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About: This article is published in European Journal of Pharmaceutics and Biopharmaceutics. The article was published on 01 May 2007. The article focuses on the topics: Dosage form.
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Citations
Molluscicidal activity against Biomphalaria glabrata of the bioactive nanoemulsion of the essential oil of Thymus vulgaris Linn (Thyme)
Brendha Araújo de Sousa,Ana Patrícia Matos Pereira,Paulo Victor Serra Rosa,Maria Gizelda Gomes Lages,Francisco Nascimento Silva,Larissa Karla Barros de Alencar,Maria Almira Bulcão Loureiro,Maxwell Cabral Ferreira,Thayson Lopes,Geison Luiz Costa de Castro,Ari Pereira de Araújo Neto,Gustavo Oliveira Everton +11 more
TL;DR: In this article , the molluscicidal activity against the schistosomiasis-transmitting snail (Biomphalaria glabrata) of the nanoemulsion of Thymus vulgaris L. essential oil was evaluated.
Nanoemulsion of Spiramycin against Tachyzoites of Toxoplasma gondii, RH Strain: Preparation, Toxicology, and Efficacy Studies
Saeideh Hashemi-Hafshejani,Amir Amani,Sanaz Jafarpour Azami,Hossien Keshavarz Valian,Mehdi Mohebali,Mahboobeh Salimi,Hossien Hassani Lafmejan Pour,Saeedeh Shojaee +7 more
TL;DR: NE-Spi has lethal efficacy on T. gondii RH strain in-vitro, and the highest mortality rates of tachyzoites of T.gondii, RH strain were observed at 250 µg/ml concentration and after 120 min of exposure, but it was not significantly different from 24 h of exposure.
Lipid-Gelucire based rectal delivery of ramipril prodrug exhibits significant lowering of intra-ocular pressure in normotensive rabbit: Sustained structural relaxation release kinetics and IVIVC.
Souvik Nandi,Rakesh Keshari Swain,Sk Habibullah,Rudra Narayan Sahoo,Amit Kumar Nayak,Subrata Mallick +5 more
- 25 Apr 2024
TL;DR: The pharmacodynamic bioavailability of ramipril has been improved significantly using a sustained-release rectal suppository and a rectal suppository for sustained delivery of ramipril could be used to lower IOP significantly.
Pseudoternary phase diagrams used in emulsion preparation
Vikas Jhawat,Monika Gulia,Anil Kumar Sharma +2 more
- 01 Jan 2021
TL;DR: The pseudoternary phase diagram as mentioned in this paper can predict the type of emulsion formed, globule size, miscibility, phase behavior, and ultimately thermodynamic stability of the emulsion.
Self nanoemulsifying drug delivery system of stabilized ellagic acid–phospholipid complex with improved dissolution and permeability
Amelia M. Avachat,Vijay G. Patel +1 more
TL;DR: In this study, a new self-nanoemulsifying drug delivery system (SNEDDS), based on the phospholipid complex technique, was developed to improve the oral bioavailability of ellagic acid to overcome the food effect shown by EA suspension.
References
Effects of an angiotensin-converting -enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients
TL;DR: Ramipril significantly reduces the rates of death, myocardial infarction, and stroke in a broad range of high-risk patients who are not known to have a low ejection fraction or heart failure.
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A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability
TL;DR: A biopharmaceutics drug classification scheme for correlating in vitro drug product dissolution and in vivo bioavailability is proposed based on recognizing that drug dissolution and gastrointestinal permeability are the fundamental parameters controlling rate and extent of drug absorption.
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James Swarbrick
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TL;DR: Compounding, Contemporary, andProcess Chemistry in the Pharmaceutical Industry: Characterization and Function, Volume 19.
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Microemulsion-based media as novel drug delivery systems
M. Jayne Lawrence,Gareth D. Rees +1 more
TL;DR: The use of microemulsions and closely related microemulsion-based systems as drug delivery vehicles is reviewed, with particular emphasis being placed on recent developments and future directions.
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Nano-emulsion formulation using spontaneous emulsification: solvent, oil and surfactant optimisation
TL;DR: This phase of emulsion optimisation represents an important step in the process of polymeric nanocapsules preparation using nanoprecipitation or interfacial polycondensation combined with spontaneous emulsification technique.
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