Journal Article10.1016/J.EJPB.2006.10.014
Development and bioavailability assessment of ramipril nanoemulsion formulation.
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TL;DR: The present study revealed that ramipril nanoemulsion could be used as a liquid formulation for pediatric and geriatric patients and can be formulated as self-nanoemulsifying drug delivery system (SNEDDS) as a unit dosage form.
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About: This article is published in European Journal of Pharmaceutics and Biopharmaceutics. The article was published on 01 May 2007. The article focuses on the topics: Dosage form.
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Peer Review
Microemulsion –A Multidimensional Formulation
TL;DR: In this article , the authors reviewed the structure of microemulsion and their components like oil, surfactant, cosurfactant and water and discussed the multiple importance of micromulsion.
SELF-EMULSIFYING DRUG DELIVERY SYSTEM: A NOVEL APPROACH Review Article
Naisarg D. Pujara
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TL;DR: How self-emulsifying drug delivery systems can increase the solubility and bioavailability of poorly soluble drug is explained.
Patent
Compound ramipril nano-emulsion for antihypertension
Wuqing Ouyang,Jianghong Sun,Xingxing Zheng,Xiaohua Zhang,Tiangang Yuan +4 more
- 25 Apr 2012
TL;DR: In this paper, an oil-in-water type compound ramipril nano-emulsion, which is prepared from 1%-25% of Ramipril, 0.1%-15% of lisinopril, 10%-55% of surfactant, 5%-30% of oil and the balance distilled water, wherein the sum of the mass percent of the ingredients is 100%.
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Design, Development and Evaluation of Self Nanoemulsifying Drug Delivery System of Garlic Oil using Capryol PGMC
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TL;DR: The bioavailability problem can be overcome by the Self nanoemulsifying drug delivery system, which presents the more drug in solubilized form in the body as compared with other conventional drug delivery systems.
References
Effects of an angiotensin-converting -enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients
TL;DR: Ramipril significantly reduces the rates of death, myocardial infarction, and stroke in a broad range of high-risk patients who are not known to have a low ejection fraction or heart failure.
8.4K
A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability
TL;DR: A biopharmaceutics drug classification scheme for correlating in vitro drug product dissolution and in vivo bioavailability is proposed based on recognizing that drug dissolution and gastrointestinal permeability are the fundamental parameters controlling rate and extent of drug absorption.
•Book
Encyclopedia of Pharmaceutical Technology
James Swarbrick
- 01 Oct 2006
TL;DR: Compounding, Contemporary, andProcess Chemistry in the Pharmaceutical Industry: Characterization and Function, Volume 19.
3K
Microemulsion-based media as novel drug delivery systems
M. Jayne Lawrence,Gareth D. Rees +1 more
TL;DR: The use of microemulsions and closely related microemulsion-based systems as drug delivery vehicles is reviewed, with particular emphasis being placed on recent developments and future directions.
1.9K
Nano-emulsion formulation using spontaneous emulsification: solvent, oil and surfactant optimisation
TL;DR: This phase of emulsion optimisation represents an important step in the process of polymeric nanocapsules preparation using nanoprecipitation or interfacial polycondensation combined with spontaneous emulsification technique.
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