Journal Article10.1021/ACSBIOMATERIALS.6B00766
Development and Antibacterial Performance of Novel Polylactic Acid-Graphene Oxide-Silver Nanoparticle Hybrid Nanocomposite Mats Prepared by Electrospinning
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TL;DR: Novel PLA-based fibrous mats with GO-Ag hybrid nanofillers through electrospinning for minimizing bacterial attachment and growth for biomedical applications and systematically depicts the bactericidal mechanism of PLA-GO-Ag nanocomposites are developed.
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Abstract: Antibacterial nanomaterials have attracted great interest in recent years, especially with an increase in antibiotic resistance of microbial organisms. However, deleterious properties such as aggregation, toxicity of nanoparticles, and low stability limit their practical application. In this respect, we have developed novel PLA-based fibrous mats with GO-Ag hybrid nanofillers through electrospinning for minimizing bacterial attachment and growth for biomedical applications. Polylactic acid (PLA) exhibits low tensile modulus and strength as well as no bactericidal ability. To enhance its tensile and bactericidal performances, 1 wt % graphene oxide (GO), and 1–7 wt % silver nanoparticle (AgNP) are incorporated into the PLA matrix. For comparison, electrospun PLA-1 wt % GO and PLA-AgNP nanocomposites have also been prepared. The morphological, mechanical and thermal properties as well as bactericidal activities of electrospun PLA-based nanocomposite fibrous mats have been investigated. Tensile tests show tha...
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Electrospun Polyvinylidene Fluoride-Based Fibrous Scaffolds with Piezoelectric Characteristics for Bone and Neural Tissue Engineering.
TL;DR: Recent development strategies, achievements and major challenges of electrospun PVDF and P(VDF-TrFE) scaffolds for tissue engineering applications are reviewed.
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Antimicrobial nanofillers reinforced biopolymer composite films for active food packaging applications - a review
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