Journal Article10.1002/MDS.20955
Deep brain stimulation: preoperative issues.
Anthony E. Lang,J. L. Houeto,Paul Krack,Cynthia S. Kubu,Kelly E. Lyons,Elena Moro,William G. Ondo,Rajesh Pahwa,Werner Poewe,Alexander I. Tröster,Ryan J. Uitti,Valerie Voon,Valerie Voon +12 more
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TL;DR: The Consensus on Deep Brain Stimulation for Parkinson's Disease outlines answers to a series of questions developed to address all aspects of deep brain stimulation preoperative decision‐making.
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Abstract: Numerous factors need to be taken into account in deciding whether a patient with Parkinson's disease (PD) is a candidate for deep brain stimulation. Patient-related personal factors including age and the presence of other comorbid disorders need to be considered. Neuropsychological and neuropsychiatric concerns relate both to the presurgical status of the patient and to the potential for surgery to result in new problems postoperatively. A number of factors related to the underlying PD need to be considered, including the specific parkinsonian motor indications (e.g., tremor, bradykinesia, gait dysfunction), previous medical therapies, including benefit from current therapy and adverse effects, and past surgical treatments. Definable causes of Parkinsonism, particularly atypical Parkinsonisms, should be considered. Finally, methods of evaluating outcomes should be defined and formalized. This is a report from the Consensus on Deep Brain Stimulation for Parkinson's Disease, a project commissioned by the Congress of Neurological Surgeons and the Movement Disorder Society (MDS). The report has been endorsed by the Scientific Issues Committee of the MDS and the American Society of Stereotactic and Functional Neurosurgery. It outlines answers to a series of questions developed to address all aspects of deep brain stimulation preoperative decision-making.
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Citations
Bilateral Deep Brain Stimulation vs Best Medical Therapy for Patients With Advanced Parkinson Disease: A Randomized Controlled Trial
Frances M. Weaver,Frances M. Weaver,Kenneth A. Follett,Matthew B. Stern,Matthew B. Stern,Kwan Hur,Crystal L. Harris,William J. Marks,William J. Marks,Johannes C. Rothlind,Johannes C. Rothlind,Oren Sagher,Domenic J. Reda,Claudia S. Moy,Rajesh Pahwa,Kim J. Burchiel,Kim J. Burchiel,Penelope Hogarth,Penelope Hogarth,Eugene C. Lai,Eugene C. Lai,John E. Duda,John E. Duda,Kathryn L. Holloway,Kathryn L. Holloway,Ali Samii,Stacy Horn,Jeff M. Bronstein,Gatana Stoner,Jill Heemskerk,Grant D. Huang +30 more
TL;DR: Deep brain stimulation was more effective than best medical therapy in improving on time without troubling dyskinesias, motor function, and quality of life at 6 months, but was associated with an increased risk of serious adverse events.
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Deep Brain Stimulation for Parkinson Disease: An Expert Consensus and Review of Key Issues
Jeff M. Bronstein,Michele Tagliati,Ron L. Alterman,Andres M. Lozano,Jens Volkmann,Alessandro Stefani,Fay B. Horak,Michael S. Okun,Kelly D. Foote,Paul Krack,Rajesh Pahwa,Jaimie M. Henderson,Marwan Hariz,Roy A.E. Bakay,Ali R. Rezai,William J. Marks,Elena Moro,Jerrold L. Vitek,Frances M. Weaver,Robert E. Gross,Mahlon R. DeLong +20 more
TL;DR: Recommendations are provided to patients, physicians, and other health care providers on several issues involving deep brain stimulation (DBS) for Parkinson disease (PD) to be considered in a select group of appropriate patients.
Cognitive sequelae of subthalamic nucleus deep brain stimulation in Parkinson's disease: a meta-analysis
TL;DR: After adjusting for heterogeneity of variance in study effect sizes, the random effects meta-analysis revealed significant, albeit small, declines in executive functions and verbal learning and memory after STN DBS.
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