Journal Article10.1002/MDS.20957
Deep brain stimulation: postoperative issues.
Günther Deuschl,Jan Herzog,Galit Kleiner-Fisman,Cynthia S. Kubu,Andres M. Lozano,Kelly E. Lyons,Maria C. Rodriguez-Oroz,Filippo Tamma,Alexander I. Tröster,Jerrold L. Vitek,Jens Volkmann,Valerie Voon +11 more
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TL;DR: Answer to a series of questions developed to address all aspects of DBS postoperative management and decision‐making with a systematic overview of the literature are outlined.
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Abstract: Numerous factors need to be taken into account when managing a patient with Parkinson's disease (PD) after deep brain stimulation (DBS). Questions such as when to begin programming, how to conduct a programming screen, how to assess the effects of programming, and how to titrate stimulation and medication for each of the targeted sites need to be addressed. Follow-up care should be determined, including patient adjustments of stimulation, timing of follow-up visits and telephone contact with the patient, and stimulation and medication conditions during the follow-up assessments. A management plan for problems that can arise after DBS such as weight gain, dyskinesia, axial symptoms, speech dysfunction, muscle contractions, paresthesia, eyelid, ocular and visual disturbances, and behavioral and cognitive problems should be developed. Long-term complications such as infection or erosion, loss of effect, intermittent stimulation, tolerance, and pain or discomfort can develop and need to be managed. Other factors that need consideration are social and job-related factors, development of dementia, general medical issues, and lifestyle changes. This report from the Consensus on Deep Brain Stimulation for Parkinson's Disease, a project commissioned by the Congress of Neurological Surgeons and the Movement Disorder Society, outlines answers to a series of questions developed to address all aspects of DBS postoperative management and decision-making with a systematic overview of the literature (until mid-2004) and by the expert opinion of the authors. The report has been endorsed by the Scientific Issues Committee of the Movement Disorder Society and the American Society of Stereotactic and Functional Neurosurgery.
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Citations
Deep brain stimulation of the subthalamic nucleus for the treatment of Parkinson's disease
TL;DR: High-frequency deep brain stimulation of the subthalamic nucleus is a powerful method that is currently unchallenged in the management of Parkinson's disease, but its long-term effects must be thoroughly assessed.
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An optical neural interface: in vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology
Alex Aravanis,Liping Wang,Feng Zhang,Leslie Meltzer,Murtaza Mogri,M. Bret Schneider,Karl Deisseroth +6 more
TL;DR: The first in vivo behavioral demonstration of a functional optical neural interface (ONI) in intact animals is reported, involving integrated fiberoptic and optogenetic technology and may find application across a broad range of neuroscience, neuroengineering and clinical questions.
Closed-Loop Deep Brain Stimulation Is Superior in Ameliorating Parkinsonism
Boris Rosin,Maya Slovik,Rea Mitelman,Rea Mitelman,Michal Rivlin-Etzion,Michal Rivlin-Etzion,Suzanne N. Haber,Zvi Israel,Eilon Vaadia,Eilon Vaadia,Hagai Bergman,Hagai Bergman +11 more
TL;DR: Closed-loop DBS paradigms, by modulating pathological oscillatory activity rather than the discharge rate of the BG-cortical networks, may afford more effective management of advanced PD.
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Cognition and mood in Parkinson's disease in subthalamic nucleus versus globus pallidus interna deep brain stimulation: The COMPARE Trial†
Michael S. Okun,Hubert H. Fernandez,Samuel S. Wu,Lindsey Kirsch-Darrow,Dawn Bowers,Frank J. Bova,Michele Suelter,Charles E. Jacobson,Xinping Wang,Clifford W. Gordon,Pamela Zeilman,Janet Romrell,Pamela Martin,Herbert E. Ward,Ramon L. Rodriguez,Kelly D. Foote +15 more
TL;DR: The cognitive and mood effects of subthalamic nucleus (STN) vs. globus pallidus interna (GPi) deep brain stimulation (DBS) in Parkinson disease is compared in a prospective blinded study.
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Basic algorithms for the programming of deep brain stimulation in Parkinson's disease
TL;DR: A stepwise and standardized approach is outlined, reducing the possible parameter settings in DBS to a few relevant combinations, explaining the basic programming algorithms for thalamic, subthalamic, and pallidal stimulation in PD.
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