Journal Article10.5754/HGE11182
Decrease in size of non-treated lesions after cryoablation for hepatocellular carcinoma.
Lin Zhou,Chunping Wang,Yinying Lu,Wenlin Bai,Jianhui Qu,Min Lou,Zhen Zeng,Yu Wu,Yan Chen,Hong Wang,Xiujuan Chang,Yong-ping Yang +11 more
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TL;DR: The case of one 58-year-old man with advancd hepatocellular carcinoma and hepatitis-B virus-related liver cirrhosis who received hepatic cryoablation, who remains in good condition until now.
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Abstract: We present the case of one 58-year-old man with advancd hepatocellular carcinoma and hepatitis-B virus-related liver cirrhosis who received hepatic cryoablation. Magnetic resonance imaging (MRI) showed multiple liver tumors and the diameter of the largest tumor was more than 10cm. The patient received 2 percutaneous cryoablations in December 2009 and January 2010. Ten months later, MRI showed that not only the treated areas underwent necrosis but also the non-treated area decreased. The a-fetoprotein (AFP) level and the frequency of circulated regulatory T cell (Treg) before treatment were 13,800ng/mL and 15.6%, respectively. Following the cryoablations they dropped to 436ng/mL and 7.6%, respectively, 10 months later. The patient remains in good condition until now.
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EASL and mRECIST responses are independent predictors of survival in hepatocellular carcinoma patients treated with cryoablation
TL;DR: The enhancement models including mRECIST and EASL guidelines should be used in preference to WHO, RECIST 1.1, or target responses to assess the efficacy of cryotherapy.
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