Decrease in hepatitis B prevalence among blood donors in Central-West Brazil
Andrea de Siqueira Campos Lindenberg,Ana Rita Coimbra Motta-Castro,Marco Antonio Moreira Puga,Tayana Serpa Ortiz Tanaka,Marina Sawada Torres,Sonia M. Fernandes-Fitts,Rivaldo Venancio da Cunha +6 more
TL;DR: The seroprevalence of HBV infection in first-time blood donors diminished from 2001 to 2010, which suggests an improvement in the recruitment of safe donors, the positive impact of vaccination programs and the decreasing ofHBV infection prevalence in the general population.
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Abstract: Background: The aim of the present study was to estimate hepatitis B virus seroprevalence among first-time blood donors in the city of Campo Grande, Mato Grosso do Sul State, in the central-western region of Brazil. Findings: A retrospective analysis of first-time voluntary blood donor records, from January 2010 to December 2010, was conducted at the Hematology Center of Mato Grosso do Sul. The prevalence of the HBsAg and anti-HBc serological markers and their respective 95% confidence intervals were calculated. Chi-square analysis was performed between the seroprevalence previously found in 2001 and the one determined by the current study. Results were considered statistically significant if p < 0.05. Among 8,840 subjects, 269 (3.04%, 95% CI: 2.7-3.4) were positive for HBV markers. The prevalence rate of HBsAg was 0.19% (95% CI: 0.1-0.3) and anti-HBc alone was 2.85% (95% CI: 2.5-3.2). Conclusions: There was no statistically significant difference regarding gender. However, an important association was observed between HBV infection and older age (p < 0.01). The seroprevalence of HBV infection in first-time blood donors diminished from 2001 to 2010 (p < 0.01). Such decrease suggests an improvement in the recruitment of safe donors, the positive impact of vaccination programs and the decreasing of HBV infection prevalence in the general population.
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Citations
Prevalence and trends in transfusion-transmissible infections among blood donors in Brazil from 2010 to 2016
TL;DR: Even with the reduction in HBV, the increased rate of syphilis may have contributed to the fact that the overall rate of TTIs did not decrease in the evaluated period.
Prevalence and Incidence of HCV Infection among Prisoners in Central Brazil
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TL;DR: Assessment of the prevalence, incidence and associated risk factors among incarcerated populations from twelve Brazilian prisons showed independent associations between HCV exposure and increasing age, inject drug use, length of incarceration, smoking hashish, sharing needle and syringe and HIV positivity among men prisoners.
High level of exposure to hepatitis B virus infection in a vulnerable population of a low endemic area: A challenge for vaccination coverage.
Sabrina Moreira dos Santos Weis-Torres,Sonia Maria Fernandes Fitts,Wesley Márcio Cardoso,Minoru German Higa Júnior,Livia Alves Lima,Larissa Melo Bandeira,Vivianne de Oliveira Landgraf de Castro,Fátima Aparecida Carneiro,Luciana Maria Marangoni Iglecias,Gabriela Alves Cesar,Tayana Serpa Ortiz Tanaka,Marco Antonio Moreira Puga,Grazielli Rocha de Rezende,Julio Croda,Barbara Vieira do Lago,Ana Rita Coimbra Motta-Castro +15 more
TL;DR: Despite the availability and efficacy of HBV vaccine, this study found high HBV exposure and proportion of susceptible adults in a low endemic area and vaccination and screening campaigns using accessible language to the economically disadvantaged populations can reduce the number of people susceptible to HBV infection.
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Hepatitis B Virus Infection and Associated Factors among Blood Donors at Dire Dawa, Eastern Ethiopia
TL;DR: The prevalence of HBV infection in this study is high and the disease is still a major health problem in the region which calls for high alert public health intervention.
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Prevalence of hepatitis B virus, hepatitis C virus, and human immunodeficiency virus among blood donors of Mekelle blood bank, Northern Ethiopia: A three-year retrospective study
Berhanu Degefa,Teklehaymanot Gebreeyesus,Zufan Gebremedhin,Getachew Melkamu,Atsebaha Gebrekidan,Haftamu Hailekiros,Ephrem Tsegay,Selam Niguse,Mahmud Abdulkader +8 more
TL;DR: A significant association between sex and marital status with HBV and HIV infection was found, and a significant percentage of HBV, HCV, and HIV among blood donors was observed.
17
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