Cyanoacrylate for Intraoral Wound Closure: A Possibility?
TL;DR: Isoamyl cyanoacrylate can be used for intraoral wound closure, as an alternative to sutures for gluing the mucoperiosteum to bone, for example, after impaction removal, periapical surgeries, and cleft repair.
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Abstract: Wound closure is a part of any surgical procedure and the objective of laceration repair or incision closure is to approximate the edges of a wound so that natural healing process may occur. Over the years new biomaterials have been discovered as an alternate to conventional suture materials. Cyanoacrylate bioadhesives are one among them. They carry the advantages of rapid application, patient comfort, resistance to infection, hemostatic properties, and no suture removal anxiety. Hence this study was undertaken to study the effect of long chain cyanoacrylate as an adhesive for intraoral wound closure and also to explore its hemostatic and antibacterial effects. Isoamyl-2-cyanoacrylate (AMCRYLATE) was used as the adhesive in the study. In conclusion isoamyl cyanoacrylate can be used for intraoral wound closure, as an alternative to sutures for gluing the mucoperiosteum to bone, for example, after impaction removal, periapical surgeries, and cleft repair. Its hemostatic and antibacterial activity has to be further evaluated.
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Citations
Oral Applications of Cyanoacrylate Adhesives: A Literature Review.
TL;DR: In vivo and clinical studies have demonstrated in the last few years convincing results regarding the safety, efficacy, ease of application, and feasibility of all types of cyanoacrylate adhesives used in intra- and extraoral procedures.
Bio-macromolecular design roadmap towards tough bioadhesives.
H. Montazerian,Elham Davoodi,Avijit Baidya,Maryam Badv,Reihaneh Haghniaz,Arash Dalili,Abbas S. Milani,Mina Hoorfar,Nasim Annabi,Ali Khademhosseini,Paul S. Weiss +10 more
TL;DR: In this paper , the authors provide a biomacromolecular design roadmap for the development of tough adhesive surgical sealants and discuss a library of materials and methods to introduce toughness and adhesion to biomaterials.
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Comparison between N-butyl cyanoacrylate tissue adhesive and Ethilon nylon sutures in extraoral maxillofacial incisions: A randomized prospective study
Sudipto Sahu,Sobhan Mishra,Sthitaprajna Lenka,Rajarshi Banerjee,Sandeep Pachisia,Sucharu Ghosh +5 more
TL;DR: Advantages of tissue adhesives over conventional wound closure techniques include easy to use, excellent bacteriostatic property, decreased repair time, elimination of recall visits and comparable short and long-term cosmetic outcome.
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Current status of split-mouth controlled clinical trials comparing cyanoacrylate vs. conventional suture after lower third molar surgeries: a systematic literature review
Ana Federica Stran-Lo Giudice,Azahara María Ortiz,Luis Sánchez-Labrador,Jorge Cortés-Bretón Brinkmann,Carlos Cobo-Vázquez,Cristina Meniz-García +5 more
TL;DR: In this paper , the authors compared the effects of using cyanoacrylate and sutures for wound closure in lower third molar (LTM) removal with four studies.
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Efficacy of Sub-Gingivally Delivered Propolis Nanoparticle in Non-Surgical Management of Periodontal Pocket: A Randomized Clinical Trial
Sushree Ambika Sahu,Saurav Panda,Abhaya Chandra Das,Lora Mishra,Satchidananda Rath,Krzysztof Sokolowski,Manoj Kumar,Rinkee Mohanty,Rashmi Nayak,Anurag Satpathy,Barbara Lapinska +10 more
TL;DR: The subgingival delivery of propolis nanoparticles showed promising results as an adjunct to SRP in patients with periodontitis presenting periodontal pockets.
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TL;DR: It is demonstrated that octylcyanoacrylate can be used successfully in a wide variety of clinical and surgical settings for multiple types of wounds covering most of the surface of the human body.
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Cyanoacrylate Adhesive Used to Stop CSF Leaks During Orbital Surgery
TL;DR: Butyl-2-cyanoacrylate (Histoacryl Blue) tissue adhesive successfully sealed three cases of CSF leaks encountered during orbital surgery and has been found to be a valuable technical adjunct in the intraoperative management of this difficult problem.
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Cyanoacrylate adhesive for closing sinus membrane perforations during sinus lifts
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TL;DR: These results support the clinical use of cyanoacrylate adhesive for repairing sinus membrane perforations and show newly formed continuous epithelium across the previous perforation site.
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Use of N-butyl-2-cyanoacrylate in elective surgical incisions--longterm outcomes.
TL;DR: Administration of N-butyl-2-cyanoacrylate for the closure of small low-tension surgical incisions in the pediatric population is safe, has a low complication rate, and produces excellent cosmetic outcomes.
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