Journal Article10.1016/0022-2836(87)90689-9
CpG islands in vertebrate genomes.
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TL;DR: It is shown that CpG islands in methylated genomes are maintained, despite a tendency for 5mCpG to mutate by deamination to TpG+CpA, by the structural stability of a high G+C content alone, and that C pG islands associated with exons result from some selective importance of the arginine codon CGX.
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About: This article is published in Journal of Molecular Biology. The article was published on 20 Jul 1987. The article focuses on the topics: CpG site & Differentially methylated regions.
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Initial sequencing and comparative analysis of the mouse genome.
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