Coronary Artery Calcification: Pathophysiology, Epidemiology, Imaging Methods, and Clinical Implications

TL;DR: The observed expression patterns suggest a tight regulation of the expression of bone matrix regulatory proteins during human atherogenesis, which might suggest a regulatory role of these proteins not only in osteoclastogenesis but also in atherosclerotic calcification.

TL;DR: Waist-to-hip ratio, smoking, hypertension, and hypercholesterolemia, before or at the time of CT, were significantly associated with CAC in univariate and multivariate analyses and CAC was associated with mean HbA1c levels before enrollment, during the DCCT, and during the EDIC study.

TL;DR: It is found that CAC progression correlates with worsening atherosclerosis and may facilitate prediction of future cardiac events and support the notion that slowing CAC progress with therapeutic interventions might provide prognostic benefit.

TL;DR: It is suggested that a high hostility level may predispose young adults to coronary artery calcification, which is a marker of subclinical atherosclerosis.

TL;DR: Choi et al. as discussed by the authors examined the relationship between dietary cholesterol intake and coronary artery calcification (CAC) score in healthy men and found that high cholesterol intake was significantly related to a high CAC score (OR 1.12: 95% Cl 1.02 - 1.24).

TL;DR: In this paper, a cinecoronariografia de torax was used to verify concordância entre a presenca de calcio no botao aortico vista in radiografias simples of torax em posicao postero-anterior and a existencia of ateromasia coronariana.

TL;DR: Multisection spiral CT enables coronary calcium quantification with high reproducibility in follow-up examinations mainly founded on image data with reduced partial-volume errors due to overlapping increment.

TL;DR: The importance of genetic factors in subclinical coronary atherosclerosis variation as measured by CAC quantity shows the presence of genetic effects and suggests that unknown genes that influence CAC quantities are yet to be identified.