Journal Article10.1039/C5CC05821J
Copper-mediated three-component synthesis of 3-cyanoimidazo[1,2-a]pyridines.
TL;DR: A copper-mediated three-component approach towards the synthesis of 3-cyanoimidazo[1,2-a]pyridine from 2-aminopyridines, acetophenones and benzyl cyanide was developed.
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About: This article is published in Chemical Communications. The article was published on 08 Oct 2015. The article focuses on the topics: Cyanation & Benzyl cyanide.
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Citations
Recent Advances in the Synthesis of Aryl Nitrile Compounds
TL;DR: A review of the recent developments and useful applications in this field and their mechanisms are also briefly discussed in this article, where aryl nitriles are found wide applications in natural products, pharmaceuticals, agrochemicals, dyes, and herbicides.
243
Sodium Salts (NaI/NaBr/NaCl) for the Halogenation of Imidazo-Fused Heterocycles.
TL;DR: An effective method for the halogenation of imidazo-fused heterocycles using readily available sodium salts (NaCl/NaBr/NaI) as halogen source and K2S2O8 (or) oxone as promoter is reported.
108
Copper-Catalyzed Three-Component System for Arylsulfenylation of Imidazopyridines with Elemental Sulfur
Chitrakar Ravi,N. Naresh Kumar Reddy,Venkatanarayana Pappula,Supravat Samanta,Subbarayappa Adimurthy +4 more
TL;DR: A one-pot three-component reaction for the regioselective synthesis of thioarylated imidazoheterocycles from aryl halides and elemental sulfur using copper(I) iodide as a catalyst has been developed.
91
Synthesis of Imidazo[1,2-a]pyridines: C-H Functionalization in the Direction of C-S Bond Formation
TL;DR: Recent efforts on the development of new methods for the synthesis of imidazo[1,2-a]pyridines using readily available starting substrates and catalysts under very mild reaction conditions are described.
76
Electrocatalytic Three-Component Reaction: Synthesis of Cyanide-Functionalization Imidazo-Fused N-Heterocycles
Peng Qian,Peng Qian,Zhenghong Zhou,Kangfei Hu,Jiawei Wang,Zhibin Li,Zhenggen Zha,Zhiyong Wang +7 more
TL;DR: An electrochemical three-component cyclization was developed under metal-free conditions, which provides a novel and facile approach for the construction of cyanide-functionalization imidazo-fused N-heterocycles.
66
References
Regioselective copper-catalyzed chlorination and bromination of arenes with O(2) as the oxidant.
TL;DR: Preliminary mechanistic insights suggest that the bromination and chlorination reactions proceed by different pathways.
Copper(I) Iodide/Boron Trifluoride Etherate‐Cocatalyzed Aerobic Dehydrogenative Reactions Applied in the Synthesis of Substituted Heteroaromatic Imidazo[1,2‐a]pyridines
TL;DR: In this article, the oxidative cyclocondensation of 2-aminopyridines with aryl alkyl ketones was investigated to provide a synthesis of imidazo[1,2-a]pyridine.