Journal Article10.1016/J.EJPB.2015.06.027
Controlled release formulations of risperidone antipsychotic drug in novel aliphatic polyester carriers: Data analysis and modelling.
Panoraia I. Siafaka,Panagiotis Barmpalexis,Maria Lazaridou,George Z. Papageorgiou,Efthimios Koutris,Evangelos Karavas,Margaritis Kostoglou,Dimitrios N. Bikiaris +7 more
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TL;DR: It was found that in all cases controlled release formulations were obtained, while the RISP release varies due to the properties of the used polymer blend and the different levels of drug loading.
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About: This article is published in European Journal of Pharmaceutics and Biopharmaceutics. The article was published on 01 Aug 2015. The article focuses on the topics: Controlled release & Polymer blend.
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Citations
The return of a forgotten polymer : Polycaprolactone in the 21st century
Maria A. Woodruff,Dietmar W. Hutmacher +1 more
- 01 Apr 2010
TL;DR: Polycaprolactone (PCL) was used in the biomaterials field and a number of drug-delivery devices for up to 3-4 years as discussed by the authors.
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Recent trends on wound management: New therapeutic choices based on polymeric carriers.
Mehmet Evren Okur,Ioannis D. Karantas,Zeynep Ay Şenyiğit,Neslihan Üstündağ Okur,Panoraia I. Siafaka +4 more
TL;DR: The problems that clinicians face to manage while treat acute and chronic wounds are addressed, the pathophysiology, etiology, prognosis and microbiology of wounds are demonstrated, and the state of art in pharmaceutical technology field is introduced as part of wound management.
257
Current update on nanoplatforms as therapeutic and diagnostic tools: A review for the materials used as nanotheranostics and imaging modalities.
Panoraia I. Siafaka,Neslihan Üstündağ Okur,Ioannis D. Karantas,Mehmet Evren Okur,Evren Gundogdu +4 more
TL;DR: The imaging modalities according to their use in various diseases are summarized, providing special details for radiolabeling and the most current nanotheranostics categorized via the used nanomaterials are summed up.
143
An alternative approach to wound healing field; new composite films from natural polymers for mupirocin dermal delivery.
Neslihan Üstündağ Okur,Nesrin Hökenek,Mehmet Evren Okur,Şule Ayla,Ayşegül Yoltaş,Panoraia I. Siafaka,Panoraia I. Siafaka,Erdal Cevher +7 more
TL;DR: In this study, novel adhesive films were prepared for Mupirocin dermal delivery and ex vivo bioadhesion and permeation studies using Balb-c mice were performed to check the suitability of the films.
107
Novel electrospun nanofibrous matrices prepared from poly(lactic acid)/poly(butylene adipate) blends for controlled release formulations of an anti-rheumatoid agent.
TL;DR: In vitro release studies reveal that a drug release behavior is correlated with the size of the nanofibers, drug loading and matrix degradation after a specific time and ANN dissolution modeling showed increased correlation efficacy compared to MLR.
76
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Pharmacology of risperidone (R 64 766), a new antipsychotic with serotonin-S2 and dopamine-D2 antagonistic properties.
P. A. J. Janssen,Carlos J. E. Niemegeers,Frans Awouters,K. H. L. Schellekens,Anton Megens,Theo F. Meert +5 more
TL;DR: The first clinical studies indicate that two additional therapeutic targets may be obtained with risperidone in the monotherapy of schizophrenia and related disorders: very important contact and mood-elevating properties and extrapyramidal symptoms-free maintenance therapy.
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Biochemical profile of risperidone, a new antipsychotic.
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Functional aliphatic polyesters for biomedical and pharmaceutical applications
TL;DR: This review presents the recent trends in the synthesis of functional aliphatic polyesters and their application for protein delivery and tissue engineering.
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