Contrast-enhanced, three-dimensional, whole-brain, black-blood imaging: application to small brain metastases.
Jaeseok Park,Eung Yeop Kim +1 more
TL;DR: A T1‐weighted, black‐blood version of single‐slab three‐dimensional turbo/fast spin echo whole‐brain imaging, in which the signal intensity of the brain tumor is selectively enhanced while that of blood is suppressed, is developed.
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Abstract: Contrast-enhanced three-dimensional T1-weighted imaging based on magnetization-prepared rapid-gradient recalled echo is widely used for detecting small brain metastases. However, since contrast materials remain in both blood and the tumor parenchyma and thus increase the signal intensity of both regions, it is often challenging to distinguish brain tumors from blood. In this work, we develop a T1-weighted, black-blood version of single-slab three-dimensional turbo/fast spin echo whole-brain imaging, in which the signal intensity of the brain tumor is selectively enhanced while that of blood is suppressed. For blood suppression, variable refocusing flip angles with flow-sensitizing gradients are employed. To avoid a signal loss resulting from the flow-sensitizing scheme, the first refocusing flip angle is forced to 180°. Composite restore pulses at the end of refocusing pulse train are applied to achieve partial inversion recovery for the T1-weighted contrast. Simulations and in vivo volunteer and patient experiments are performed, demonstrating that this approach is highly efficient in detecting small brain metastases. Magn Reson Med 63:553–561, 2010. © 2010 Wiley-Liss, Inc.
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Citations
Contrast enhancement of intracranial lesions at 1.5 T: comparison among 2D spin echo, black-blood (BB) Cube, and BB Cube-FLAIR sequences
Sung-Woon Im,Ryuichiro Ashikaga,Yukinobu Yagyu,Tetsuya Wakayama,Mitsuharu Miyoshi,Tomoko Hyodo,Izumi Imaoka,Seishi Kumano,Kazunari Ishii,Takamichi Murakami +9 more
TL;DR: At 1.5 T, contrast-enhanced BB Cube was a better imaging sequence for detecting brain lesions than T1W-SE or BB Cube-FLAIR and tumour detection, BB Cube showed the best detectability; however, there were no significant differences in CR among the sequences.
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Improvement of the Diagnostic Performance of Facial Neuritis Using Contrast-Enhanced 3D T1 Black-Blood Imaging: Comparison with Contrast-Enhanced 3D T1-Spoiled Gradient-Echo Imaging.
TL;DR: In this paper, the diagnostic ability of the contrastenhanced 3D T1 black-blood fast spin-echo (T1 BB-FSE) sequence compared with the contrast-enhanced three-dimensional T1-spoiled gradient echo (CE-GRE) sequence in patients with facial neuritis was investigated.
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