Book Chapter10.1007/978-3-030-57369-0_1
Constituents of Cannabis Sativa.
Erin M. Rock,Linda A. Parker +1 more
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TL;DR: This chapter provides an overview of some of the biological effects of a number of the cannabinoids and terpenes, as well as discussing their known mechanisms of action and evidence of potential therapeutic effects.
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Abstract: The Cannabis sativa plant has been used medicinally and recreationally for thousands of years, but recently only relatively some of its constituents have been identified. There are more than 550 chemical compounds in cannabis, with more than 100 phytocannabinoids being identified, including Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD). These phytocannabinoids work by binding to the cannabinoid receptors, as well as other receptor systems. Also within cannabis are the aromatic terpenes, more than 100 of which have been identified. Cannabis and its constituents have been indicated as therapeutic compounds in numerous medical conditions, such as pain, anxiety, epilepsy, nausea and vomiting, and post-traumatic stress disorder. This chapter provides an overview of some of the biological effects of a number of the cannabinoids and terpenes, as well as discussing their known mechanisms of action and evidence of potential therapeutic effects.
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Therapeutic Potential of Cannabis, Cannabidiol, and Cannabinoid-Based Pharmaceuticals
TL;DR: Data support a role for cannabis/cannabinoids in pain, seizure disorders, appetite stimulation, muscle spasticity, and treatment of nausea/vomiting, but much more careful research is required.
155
Machine learning (ML) algorithms and artificial neural network for optimizing in vitro germination and growth indices of industrial hemp (Cannabis sativa L.)
Muhammad Aasim,Ramazan Katırcı,Ozlem Akgur,Busra Yildirim,Zemran Mustafa,Muhammad Naeem,F. Baloch,Tolga Karakoy,Güngör Yilmaz +8 more
TL;DR: In this paper , the authors investigated the possible response of variable concentrations of hydrogen peroxide (H2O2) on germination and morphological traits of in vitro-grown hemp seedlings by using ML algorithms.
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Endocannabinoid System and Exogenous Cannabinoids in Depression and Anxiety: A Review
TL;DR: In this paper , the authors explore the association between depression or anxiety and dysregulation of the endogenous endocannabinoid system (ECS), as well as the use of phytocannabinoids and synthetic cannabinoids in the remediation of depression/anxiety symptoms.
Cannabis sativa Cannabinoids as Functional Ingredients in Snack Foods—Historical and Developmental Aspects
TL;DR: In this article , the distribution of nutrients and phytocannabinoids in low-THC Cannabis sativa, the historical uses of hemp, cannabis edibles, and the possible side-effects and concerns related to cannabis edible.
The effects of cannabis and cannabinoids on the endocrine system
Farah Meah,Michelle D. Lundholm,Nicholas V. Emanuele,Hafsa Amjed,Caroline A Poku,Lily Agrawal,Mary Ann Emanuele +6 more
TL;DR: In this paper, a review summarizes the known impacts of cannabis on thyroid, adrenal, and gonadal function in addition to glucose control, lipids, and bone metabolism, including: reduced female fertility, increased risk of adverse pregnancy outcomes, reduced sperm counts and function, lower thyroid hormone levels with acute use, blunting of stress response with chronic use, increasing risk of prediabetes but lower risk of diabetes, suggested improvement of high density lipoproteins and triglycerides, and modest increase in fracture risk.
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