Comparison of social cognitive functioning in schizophrenia and high functioning autism: More convergence than divergence
TL;DR: Findings provide further support for similarities in social cognition deficits between HFA and schizophrenia, which have a variety of implications for future work on gene–brain–behavior relationships.
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Abstract: Background: Individuals with schizophrenia and individuals with high-functioning autism (HFA) seem to share some social, behavioral and biological features. Although marked impairments in social cognition have been documented in both groups, little empirical work has compared the social cognitive functioning of these two clinical groups. Method: Forty-four individuals with schizophrenia, 36 with HFA and 41 non-clinical controls completed a battery of social cognitive measures that have been linked previously to specific brain regions. Results: The results indicate that the individuals with schizophrenia and HFA were both impaired on a variety of social cognitive tasks relative to the non-clinical controls, but did not differ from one another. When individuals with schizophrenia were divided into negative symptom and paranoid subgroups, exploratory analyses revealed that individuals with HFA may be more similar, in terms of the pattern of social cognition impairments, to the negative symptom group than to the paranoia group. Conclusions: Our findings provide further support for similarities in social cognition deficits between HFA and schizophrenia, which have a variety of implications for future work on gene-brain-behavior relationships
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Citations
A Close Eye on the Eagle-Eyed Visual Acuity Hypothesis of Autism
Sven Bölte,Sven Bölte,Sabine Schlitt,Volker Gapp,Daniela Hainz,Shella Schirman,Fritz Poustka,Bernhard Weber,Christine M. Freitag,Angela Ciaramidaro,Henrik Walter +10 more
TL;DR: This study could not confirm the eagle-eyed acuity hypothesis of ASD, or find evidence for a connection of VA and clinical phenotypes, and research needs to further address the origins and circumstances associated with altered sensory or perceptual processing in ASD.
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Interpretation Bias in Paranoia: A Systematic Review and Meta-Analysis
TL;DR: A systematic review and meta-analysis of the association between interpretation bias and paranoia indicated that a negative interpretation bias was associated with paranoia both in clinical and nonclinical populations.
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Predictive waves in the autism-schizophrenia continuum: A novel biobehavioral model.
Luca Tarasi,Jelena Trajkovic,Stefano Diciotti,Giuseppe di Pellegrino,Francesca Ferri,Mauro Ursino,Vincenzo Romei +6 more
TL;DR: In this article, the authors introduce an integrated perspective that ascribes the maladjustments of the predictive mechanism to dysregulation of neural synchronization and propose a neuro-computational model capable of linking predictive coding theories with electrophysiological findings, aiming to increase knowledge on the neuronal foundations of the two spectra features.
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Clinical Profiles and Conversion Rates Among Young Individuals With Autism Spectrum Disorder Who Present to Clinical High Risk for Psychosis Services.
Jennifer H. Foss-Feig,Eva Velthorst,Lauren A. Smith,Abraham Reichenberg,Jean Addington,Kristin S. Cadenhead,Barbara A. Cornblatt,Daniel H. Mathalon,Thomas H. McGlashan,Diana O. Perkins,Larry J. Seidman,William S. Stone,Matcheri S. Keshavan,Ming T. Tsuang,Elaine F. Walker,Scott W. Woods,Tyrone D. Cannon,Carrie E. Bearden +17 more
TL;DR: It is suggested that baseline psychosis symptoms, predictors of risk for conversion, and ultimate conversion rates are similar in patients with CHR with and without ASD, and that ASD must not be considered a mutually exclusive diagnosis when such youth present in CHR settings.
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"A circle and a triangle dancing together": Alteration of social cognition in schizophrenia compared to autism spectrum disorders.
Gilles Martinez,Elise Mosconi,Claire Daban-Huard,Mara Parellada,Lourdes Fañanás,Raphaël Gaillard,M. Fatjó-Vilas,Marie-Odile Krebs,Marie-Odile Krebs,Isabelle Amado +9 more
TL;DR: In random, goal-directed and ToM conditions, persons with recent onset SCZ attributed less intentionality with less appropriate answers than HC, while the same anomalies were only found in the ToM condition in persons with ASD.
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References
The Positive and Negative Syndrome Scale (PANSS) for Schizophrenia
TL;DR: Review of five studies involving the PANSS provided evidence of its criterion-related validity with antecedent, genealogical, and concurrent measures, its predictive validity, its drug sensitivity, and its utility for both typological and dimensional assessment.
Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders
TL;DR: The revised interview has been reorganized, shortened, modified to be appropriate for children with mental ages from about 18 months into adulthood and linked to ICD-10 and DSM-IV criteria.
9K
Wechsler Abbreviated Scale of Intelligence
Ron Dumont,John O. Willis,Kathleen Veizel,Jamie Zibulsky +3 more
- 07 Feb 2014
6.6K
The Endophenotype Concept in Psychiatry: Etymology and Strategic Intentions
TL;DR: The authors discuss the etymology and strategy behind the use of endophenotypes in neuropsychiatric research and, more generally, in research on other diseases with complex genetics.
The ''Reading the Mind in the Eyes'' Test Revised Version: A Study with Normal Adults, and Adults with Asperger Syndrome or High-functioning Autism
TL;DR: The Revised Eyes Test has improved power to detect subtle individual differences in social sensitivity and was inversely correlated with the Autism Spectrum Quotient (the AQ), a measure of autistic traits in adults of normal intelligence.
5.5K