Cocoa and cardiovascular health.
TL;DR: This review summarizes the available data on the cardiovascular effects of cocoa, outlines potential mechanisms involved in the response to cocoa, and highlights the potential clinical implications associated with its consumption.
read more
Abstract: Epidemiological data demonstrate that regular dietary intake of plant-derived foods and beverages reduces the risk of coronary heart disease and stroke. Among many ingredients, cocoa might be an important mediator. Indeed, recent research demonstrates a beneficial effect of cocoa on blood pressure, insulin resistance, and vascular and platelet function. Although still debated, a range of potential mechanisms through which cocoa might exert its benefits on cardiovascular health have been proposed, including activation of nitric oxide and antioxidant and antiinflammatory effects. This review summarizes the available data on the cardiovascular effects of cocoa, outlines potential mechanisms involved in the response to cocoa, and highlights the potential clinical implications associated with its consumption.
read more
Chat with Paper
AI Agents for this Paper
Find similar papers on Google Scholar, PubMed and Arxiv
Write a critical review of this paper
Analyze citations of this paper to find unaddressed research gaps
Citations
Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity: A Comprehensive Review
TL;DR: This review considers the history, new evidence, controversies, and corresponding lessons for modern dietary and policy priorities for cardiovascular diseases, obesity, and diabetes mellitus, and identifies major identified themes.
1.9K
The Assessment of Endothelial Function From Research Into Clinical Practice
Andreas J. Flammer,Todd J. Anderson,David S. Celermajer,Mark A. Creager,Mark A. Creager,John E. Deanfield,Peter Ganz,Naomi M. Hamburg,Thomas F. Lüscher,Michael Shechter,Stefano Taddei,Joseph A. Vita,Amir Lerman +12 more
TL;DR: The assessment of its vasodilator properties resulting from NO and other molecules may provide information on the integrity and function of the endothelium, and most, if not all, cardiovascular risk factors are associated with endothelial dysfunction, and risk factor modification leads to improvement in vascular function.
1.1K
Important Flavonoids and Their Role as a Therapeutic Agent.
Asad Ullah,S M Munir,Syed Lal Badshah,Noreen Khan,Lubna Ghani,Benjamin Gabriel Poulson,Abdul-Hamid M. Emwas,Mariusz Jaremko +7 more
TL;DR: This work has made an effort to summarize the isolated flavonoids with useful activities in order to gain a better understanding of their effects on human health.
964
Bioavailability of bioactive food compounds: a challenging journey to bioefficacy
Maarit Rein,Mathieu Renouf,Cristina Cruz-Hernandez,Lucas Actis-Goretta,Sagar K. Thakkar,Marcia da Silva Pinto +5 more
TL;DR: This review focuses on some of the major factors affecting the bioavailability of the aforementioned bioactive food compounds.
Basic biochemical mechanisms behind the health benefits of polyphenols.
TL;DR: A better knowledge about the nature and biological consequences of polyphenol interactions with cell components will certainly contribute to develop nutritional and pharmacological strategies oriented to prevent the onset and/or the consequences of human disease.
717
References
Dark Chocolate Improves Coronary Vasomotion and Reduces Platelet Reactivity
Andreas J. Flammer,Frank Hermann,Isabella Sudano,Lukas E. Spieker,Matthias Hermann,Karen A. Cooper,Mauro Serafini,Thomas F. Lüscher,Frank Ruschitzka,Georg Noll,Roberto Corti +10 more
TL;DR: Dark chocolate induces coronary vasodilation, improves coronary vascular function, and decreases platelet adhesion 2 hours after consumption, paralleled by a significant reduction of serum oxidative stress and were positively correlated with changes in serum epicatechin concentration.
Cardioprotective effects of chocolate and almond consumption in healthy women
Sara Kurlandsky,Kim S. Stote +1 more
TL;DR: Consumption of chocolate and almonds as part of the Therapeutic Lifestyle Changes diet for 6 weeks showed no harmful effects in healthy women; all dietary modifications improved serum triacylglycerol levels, and consumption of chocolate reduced levels of circulating ICAM.
Breastfeeding and Risk of Inflammatory Bowel Disease.
E Klement,S Reif +1 more
TL;DR: A recent study by Baron et al found breastfeeding may increase Crohn disease risk, contradicting previous meta-analyses showing a protective effect, highlighting the need for further high-quality studies to understand the association between breastfeeding and inflammatory bowel disease.
Dark chocolate inhibits platelet aggregation in healthy volunteers
TL;DR: Dark chocolate inhibited collagen-induced platelet aggregation in platelet rich plasma, and in the future dark chocolate may have a role in prevention of cardiovascular and thromboembolic diseases.
Related Papers (5)
[...]