Cloning and Characterization of Androgen Receptor Coactivator, ARA55, in Human Prostate
Naohiro Fujimoto,Shuyuan Yeh,Hong-Yo Kang,Shigeki Inui,Hong-Chiang Chang,Atsushi Mizokami,Chawnshang Chang +6 more
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TL;DR: The cloning of a novel AR coactivator ARA55 using a yeast two-hybrid system and Northern blot and polymerase chain reaction quantitation showed ARA 55 can be expressed differently in normal prostate and prostate tumor cells suggests that ARA56 may play very important roles in the progression of prostate cancer by the modulation of AR transactivation.
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About: This article is published in Journal of Biological Chemistry. The article was published on 19 Mar 1999. and is currently open access. The article focuses on the topics: Androgen receptor & Coactivator.
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Citations
Androgen Receptor in Prostate Cancer
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TL;DR: The current review aims to provide an overview of the AR coregulator proteins identified to date and to propose a classification of these AR coreGulator proteins according to the function(s) ascribed to them, to increase the understanding of the cellular pathways that converge on the AR to ensure an appropriate transcriptional response to androgens.
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