Journal Article10.1111/J.1651-2227.1985.TB10927.X
Clinical features in hospitalised children with acute gastroenteritis. Does the rotavirus syndrome exist
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TL;DR: It is argued that upper respiratory illnesses in patients withRotavirus gastroenteritis could be due to a separate infection occurring coincidentally, and the existence of a rotavirus syndrome is questioned.
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Abstract: . In a prospective study of children referred to hospital, rotavirus was identified in 37 % of 128 patients with acute gastroenteritis. As compared with patients with non-rotavirus gastroenteritis, those with rotavirus gastroenteritis showed the following clinical characteristics: (1) Age between 5 months and 4 years. (2) Occurrence of the rotavirus infection almost exclusively during the winter season. (3) Severe vomiting. (4) Absence of gross blood in the stools. However, these signs did not form a safe basis for the clinical diagnosis of rotavirus gastroenteritis. One or more signs of upper respiratory illness were observed in 36 % of the patients with rotavirus gastroenteritis and in 35 % of those with non-rotavirus gastroenteritis. Consequently, the existence of a rotavirus syndrome is questioned. It is argued that upper respiratory illnesses in patients with rotavirus gastroenteritis could be due to a separate infection occurring coincidentally.
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Citations
Protective effect of preexisting rotavirus-specific immunoglobulin A against naturally acquired rotavirus infection in children.
TL;DR: It is recommended that studies of rotav virus vaccines include rotavirus IgA response and its protective effect and its Protective effect in children aged 6 months to 7 years.
95
Human viral gastroenteritis.
TL;DR: During the last 15 years, several different groups of fastidious viruses that are responsible for a large proportion of acute viral gastroenteritis cases have been discovered by the electron microscopic examination of stool specimens.
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Impact of acute rotavirus gastroenteritis on pediatric outpatient practices in the United States.
Susan E. Coffin,Joseph Elser,Colin D. Marchant,Mark H. Sawyer,Bernard Pollara,Ruby Fayorsey,Linda Nelson,Diane Lawley,Michelle G. Goveia,Jon E. Stek,Darcy A. Hille,Mark J. DiNubile +11 more
TL;DR: In this multicenter study, rotavirus consistently caused a sizable proportion of cases of acute gastroenteritis seen in pediatric outpatient practices in the United States during the winter and spring.
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Sequential changes in small intestinal structure and function during rotavirus infection in neonatal rats.
TL;DR: Infection causes a reversible flat mucosa resulting from enterocyte loss associated with a net secretory state for water and impaired sodium absorption as a functional correlate, which may have relevance for the pathogenesis of human rotavirus infection.
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Rotavirus-related systemic diseases: clinical manifestation, evidence and pathogenesis.
Ziqin Dian,Yi Sun,Guiqian Zhang,Ya Xu,Xin Fan,Xuemei Yang,Qiuwei Pan,Maikel P. Peppelenbosch,Zhijiang Miao +8 more
TL;DR: In this paper, the rotavirus-related extra-intestinal clinical manifestations and associated molecular pathogenesis are discussed and further understanding of the processes involved should prove exceedingly useful for future diagnosis, treatment and prevention of rotavirirus-associated disease.
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References
Importance of a new virus in acute sporadic enteritis in children
TL;DR: In a year-long survey of children admitted with acute enteritis to hospital in Melbourne, Australia, an aetiological agent was found in approximately 75% of patients, and during most months of the year a newly described virus belonging to the family Reoviridae was detected by electron microscopy of faecal extracts from more than half of patients.
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A year's experience of the rotavirus syndrome and its association with respiratory illness.
Helen Lewis,John Parry,H A Davies,Ruth P. Parry,A Mott,R R Dourmashkin,P J Sanderson,D A Tyrrell,H B Valman +8 more
TL;DR: In this paper, the rotavirus was identified in 51% of 152 children with diarrhoea and a respiratory illness was described in 66% of the patients and usually preceded the gastrointestinal symptoms.
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A year's experience oftherotavirus syndrome and its association withrespiratory illness
Helen M. Lewis,Angela Mott +1 more
- 01 Jan 1979
TL;DR: A clinician can recognise the rotavirus syndrome and expect spontaneous recovery if adequate rehydration is maintained for a critical few days.
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A prospective clinical study of rotavirus diarrhoea in young children
TL;DR: The clinical and laboratory features of 96 children aged 6 to 36 months with acute rotavirus diarrhoea were compared to findings on 63 children of the same age with acute non-rotavirus diarrhea, finding a combination of the above criteria may be helpful in the presumptive diagnosis of rotav virus diarrhoeA.
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