Journal Article10.1017/S0007114511001267
Chloroplast thylakoids reduce glucose uptake and decrease intestinal macromolecular permeability.
Caroline Montelius,Karolina Gustafsson,Björn Weström,Per-Åke Albertsson,Sinan Cem Emek,Marilyn Rayner,Charlotte Erlanson-Albertsson +6 more
TL;DR: The present results indicate that thylakoid membranes may be useful both to control intestinal absorption of glucose and to enhance the barrier function of the intestine.
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Abstract: Thylakoid membranes, derived from chloroplasts, have previously been shown to retard fat digestion and lower blood glucose levels after oral intake. The purpose of the present study was to investigate the effect of thylakoid membranes on the passage of methyl-glucose, dextran and ovalbumin over rat intestine in vitro using Ussing chambers. The results show that thylakoids retard the passage of each of the test molecules in a dose-dependent way. The thylakoids appear to be attached on the mucosal surface and a mechanism is suggested that the thylakoids delay the passage of the test molecules by sterical hindrance. The present results indicate that thylakoid membranes may be useful both to control intestinal absorption of glucose and to enhance the barrier function of the intestine.
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Citations
Functional properties of spinach (Spinacia oleracea L.) phytochemicals and bioactives
TL;DR: This review examines the functional properties of spinach in cell culture, animals and humans with a focus on the molecular mechanisms by which spinach-derived non-essential phytochemicals and bioactives, such as glycolipids and thylakoids, impart their health benefits.
215
Feeding spinach thylakoids to rats modulates the gut microbiota, decreases food intake and affects the insulin response.
Caroline Montelius,Nadia Osman,Björn Weström,Siv Ahrné,Göran Molin,Per-Åke Albertsson,Charlotte Erlanson-Albertsson +6 more
TL;DR: Findings indicate that thylakoids modulate the gut microbial composition, which might be important for the regulation of body weight and energy metabolism.
Dietary thylakoids suppress blood glucose and modulate appetite-regulating hormones in pigs exposed to oral glucose tolerance test.
Caroline Montelius,Katarzyna Szwiec,Marek Kardas,Liudmyla Lozinska,Charlotte Erlanson-Albertsson,Stefan Pierzynowski,Jens F. Rehfeld,Björn Weström +7 more
TL;DR: Dietary thylakoids may be a novel agent in reducing the glycaemic responses to high carbohydrate and high glycaemia index foods and in the future be promising for treatment and prevention of diabetes, overweight and obesity.
32
Dietary green-plant thylakoids decrease gastric emptying and gut transit, promote changes in the gut microbial flora, but does not cause steatorrhea.
Eva-Lena Stenblom,Björn Weström,Caroline Linninge,Peter Bonn,Mary Farrell,Jens F. Rehfeld,Caroline Montelius +6 more
TL;DR: Dietary supplementation with thylakoid affects satiety both via appetite hormones and GI fullness, and affects the microbial composition without causing GI adverse effects such as steatorrhea, which suggestsThylakoids as a novel agent in prevention and treatment of obesity.
The Importance of Food for Endotoxemia and an Inflammatory Response.
TL;DR: In this paper, the effect of various food components to post-prandially elevate circulating LPS and inflammatory markers is described, and the importance of food choice for endotoxemia and inflammatory response is discussed.
16
References
Determination of accurate extinction coefficients and simultaneous equations for assaying chlorophylls a and b extracted with four different solvents: verification of the concentration of chlorophyll standards by atomic absorption spectroscopy
TL;DR: In this paper, the extinction coefficients for chlorophylls a and b in diethylether (Smith, J.H. and Benitez, A.V., eds.), used in this paper as primary standards, were verified by magnesium determination using atomic absorbance spectrophotometry.
5.9K
Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies
TL;DR: The method utilizes the difference between the rate of electrophoretic migration of proteins and of their antibody complexes in agarose gel to perform quantitative analysis of proteins with a charge differing from that of the bulk of the immunoglobulins.
4.6K
Supramolecular organization of thylakoid membrane proteins in green plants.
Jan P. Dekker,Egbert J. Boekema +1 more
TL;DR: It is suggested that the margins, the strongly folded regions of the membranes that connect thegrana, are essentially protein-free, and that protein-protein interactions in the lumen also determine the shape of the grana.
918
The Dynamics of Photosynthesis
TL;DR: This work attempts to integrate well-established knowledge on the functional flexibility of light-harvesting and electron transfer processes, which has greatly benefited from genetic approaches, with data derived from the wealth of recent transcriptomic and proteomic studies of acclimation responses in photosynthetic eukaroytes.