Journal Article10.1016/J.IJBIOMAC.2019.01.192
Chitosan oligosaccharide (COS): An overview
Muhammad Naveed,Lucas Phil,Muhammad Sohail,Muhammad Hasnat,Mirza Muhammad Faran Ashraf Baig,Awais Ullah Ihsan,Muhammad Shumzaid,Mohib Ullah Kakar,Tahir Mehmood Khan,M D Akabar,Muhammad Imtiaz Hussain,Qi-Gang Zhou +11 more
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TL;DR: COS is shown to have higher cellular transduction and completely absorbable via intestinal epithelium due to its cationic sphere exposed on the more exposed shorter N-glucosamine (N-Glc) units.
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About: This article is published in International Journal of Biological Macromolecules. The article was published on 15 May 2019.
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Citations
Chitosan hydrogels in 3D printing for biomedical applications.
TL;DR: The potential application of chitosan as an ink for 3D printing, or as a coating on other 3D printed scaffolds is explored in this article, which holds much promise in the development of next generation biomedical implants.
251
Recent advancements in applications of chitosan-based biomaterials for skin tissue engineering
Ahmed Madni,Rozina Kousar,Naveera Naeem,Fazli Wahid +3 more
- 07 Jan 2021
TL;DR: This article overviewed the promising biological properties of chitosan and further discussed the various preparation methods involved in chitOSan-based biomaterials that were extensively employed in skin tissue engineering.
246
Alginate-chitosan oligosaccharide-ZnO composite hydrogel for accelerating wound healing.
TL;DR: Wang et al. as mentioned in this paper fabricated a novel sodium alginate-chitosan oligosaccharide-zinc oxide (SA-COS-ZnO) composite hydrogel by spontaneous Schiff base reaction, which can provide a moist and antibacterial environment for wound healing.
180
Preparation and biological activities of chitosan oligosaccharides
TL;DR: Compared with chitin, COSs have outstanding advantages: 1) they are easily soluble in water; 2) they have no antigenicity; 3): they have weak accumulation effect in host body.
162
Recent advances of emerging green chitosan-based biomaterials with potential biomedical applications: A review.
Ajahar Khan,Khalid A. Alamry +1 more
TL;DR: In this article, a detailed and organized description of modified chitosan and its derivatives-based nanomaterials for biomedical applications is presented. And several modification techniques and their effective utilization are also reviewed and collected in this review.
129
References
Strong electronic charge as an important factor for anticancer activity of chitooligosaccharides (COS).
TL;DR: Different charged chitosan derivatives were synthesized and their anticancer activities were studied using three cancer cell lines, HeLa, Hep3B and SW480, revealing that, highly charged COS derivatives could significantly reduce cancer cell viability, regardless to the positive or negative charge.
178
Synthesis and characterization of chitosan derivatives with dual-antibacterial functional groups.
Zhihan Li,Fei Yang,Rendang Yang +2 more
TL;DR: The zeta potential and antibacterial results indicated that the introduced quaternary ammonium and thiourea groups increased the positive charge of chitosan derivative, thereby enhanced its antibacterial activity.
172
Chitosan oligosaccharides protect mice from LPS challenge by attenuation of inflammation and oxidative stress
Ying Qiao,Xuefang Bai,Yuguang Du +2 more
TL;DR: It is demonstrated that chitosan oligosaccharides can protect mice from the LPS challenge by virtue of anti-inflammatory effects as well as anti-oxidation properties, which might offer beneficial effects for patients with sepsis.
171
Chitosan induces apoptosis via caspase-3 activation in bladder tumor cells.
TL;DR: The findings suggest that chitosan may have potential value in cancer therapy, and a growth‐inhibitory effect of chitOSan on tumor cells is reported.
Chitosan oligosaccharide as potential therapy of inflammatory bowel disease: therapeutic efficacy and possible mechanisms of action.
Mohammad Yousef,Rath Pichyangkura,Sunhapas Soodvilai,Varanuj Chatsudthipong,Chatchai Muanprasat +4 more
TL;DR: It is suggested that chitosan oligosaccharide may be effective in the treatment of IBD through inhibition of NF-κB signaling and apoptosis of intestinal epithelial cells.
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