Chitosan oligosaccharide (COS): An overview

TL;DR: Chitosan is a biotechnological derivative of chitin receiving a widespread pharmaceutical and biomedical applications and can be used to encapsulate and deliver cancer therapeutics with inherent pH-dependent solubility to confer drug targeting at tumour microenvironment and anti-cancer activity synergizing cancer cytotoxic drug actions as discussed by the authors .

TL;DR: In this paper, the role of chitosan and its nanomedicines in the treatment of chronic respiratory diseases such as pneumonia, asthma, COPD, lung cancer, tuberculosis, and COVID-19 is discussed.

TL;DR: The concepts addressed in this review have important clinical implications, although more works are needed to confirm the antidiabetic mechanisms of functional oligosaccharides, standardize safe dose levels, and clarify their metabolism in the human body.

TL;DR: In this article , the split aptamers, chitosan oligosaccharide, and AuNPs were combined as nanocomposites that present different formations to develop a label-free colorimetric aptasensor for rapid detection of small molecules.

TL;DR: In a recent study, this article showed that low cerebrospinal fluid (CSF) Aβ42 and amyloid-PET positivity precede other AD manifestations by many years.

TL;DR: In this paper, a review discusses the various attempts reported on solving this problem from the point of view of the chemistry and the structure of these polymers highlighting the drawbacks and advantages of each method and proposes that based on considerations of structure-property relations, it is possible to obtain chitin fibers with improved strength by making use of their nanostructures and/or mesophase properties of chitins.

TL;DR: These findings provide the first genetic evidence that common mutations in TLR4 are associated with differences in LPS responsiveness in humans, and demonstrate that gene-sequence changes can alter the ability of the host to respond to environmental stress.

TL;DR: A review of chitosan composites for removing dyes and heavy metal ions can be found in this article, where a list of composites with their adsorption capacity and experimental conditions has been compiled.