Journal Article10.1002/smtd.202201604
Chinese Tofu‐Inspired Biomimetic Conductive and Transparent Fibers for Biomedical Applications
Shuo Chen,Sihan Jiang,Dan Qiao,Jiangyue Wang,Qiangqiang Zhou,Chun Mao Wu,Xuefei Li,Rasoul Esmaeely Neisiany,Lijie Sun,Yuehua Liu,Zhengwei You,Meifang Zhu,Jie Pan +12 more
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TL;DR: In this paper , a new wet spinning process is established to continuously produce pure gelatin hydrogel fibers, which exhibit neuro-like features of soft-while-strong mechanical properties, high ionic conductivity, and superior biological properties including biodegradability, biocompatibility, and edibility.
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Abstract: Conductive fibers are vital for next‐generation wearable and implantable electronics. However, the mismatch of mechanical, electrical, and biological properties between existing conductive fibers and human tissues significantly retards their further development. Here, the concept of neuro‐like fibers to meet these aforementioned requirements is proposed. A new wet spinning process is established to continuously produce pure gelatin hydrogel fibers. The key is the controllable and rapid gelation of spinning solutions based on the salting‐out effect, which is inspired by the Chinese food tofu. The resultant fibers exhibit neuro‐like features of soft‐while‐strong mechanical properties, high ionic conductivity, and superior biological properties including biodegradability, biocompatibility, and edibility, which are crucial for implanted applications but seldom reported. Furthermore, all‐weather suitable neuro‐like fibers with excellent anti‐freezing and water retention properties are developed by introducing glycerol for wearable applications. The optical fiber, transient electronics, and electronic data glove made of neuro‐like fibers profoundly demonstrate their potential in biomedical applications.
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Citations
Continuous Melt Spinning of Covalently Cross-Linked Self-Healing Ionogel Fibers for Multi-Functional Ionotronics.
Hui Tan,Lijie Sun,Hongfei Huang,Luzhi Zhang,Rasoul Esmaeely Neisiany,Xiaopeng Ma,Zhengwei You +6 more
TL;DR: Continuous melt spinning of covalently cross-linked self-healing ionogel fibers for multi-functional ionotronics enables high transparency, stretchability, conductivity, solvent resistance, and self-healing ability.
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Innovations in spider silk‐inspired artificial gel fibers: Methods, properties, strengthening, functionality, and challenges
A. Q. Khan,Wenjin Guo,Sitong Li,Yutian Zhu,Jie Bai,Zunfeng Liu,Wei Zhao,Xiang Zhou +7 more
TL;DR: Innovations in spider silk-inspired artificial gel fibers focus on improving performance and functionalizing applications. The review covers design, properties, strengthening, and functionalities of gel fibers, highlighting their potential in diverse fields. Challenges remain in optimizing and functionalizing gel fibers.
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Metal-organic framework-hydrogel composites as emerging platforms for enhanced wound healing applications: Material design, therapeutic strategies, and future prospects
Fereshte Hassanzadeh‐Afruzi,Majid Abdouss,Ehsan Nazarzadeh Zare,Erfan Rezvani Ghomi,Seyed Reza Mahmoudi,Rasoul Esmaeely Neisiany +5 more
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Human Adipose Tissue Lysate-Based Hydrogel for Lasting Immunomodulation to Effectively Improve Spinal Cord Injury Repair.
Yu Wang,Ying-Qian Chai,Jie Cai,Shan-Shan Huang,Ye-Feng Wang,Shan-Shan Yuan,Ji-Long Wang,Ke-Qing Shi,Jun-Jie Deng +8 more
TL;DR: Human adipose tissue lysate-based hydrogel (HATLH) with an appropriate degradation rate is developed, which aims to in situ long-term recruit and induce anti-inflammatory M2 macrophages through sustainedly released proteins.
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Functionalized hydrogels as smart gene delivery systems to treat musculoskeletal disorders
M.H. Enayati,Wei Liu,Henning Madry,Rasoul Esmaeely Neisiany,Magali Cucchiarini +4 more
TL;DR: Functionalized hydrogels are a promising platform for gene therapy in treating musculoskeletal disorders due to their versatility, injectability, stimuli-responsiveness, and self-healing properties.
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TL;DR: It is shown that a wearable sign-to-speech translation system, assisted by machine learning, can accurately translate the hand gestures of American Sign Language into speech.
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TL;DR: Anti-freezing conductive organohydrogels are reported by using an H2 O/ethylene glycol binary solvent as dispersion medium with non-covalent crosslinks to exhibit stable flexibility and strain-sensitivity in the temperature range from -55.0 to 44.6 °C.
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Materials and technologies for soft implantable neuroprostheses
TL;DR: This review discusses materials-based approaches to overcome the physical and mechanical mismatch at the tissue–implant interface and to design long-term neurointegrated prostheses.