Journal Article10.1038/s41572-022-00337-x
Childhood stroke
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About: This article is published in Nature Reviews Disease Primers. The article was published on 24 Feb 2022. The article focuses on the topics: Stroke (engine) & Medicine.
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Citations
Endovascular thrombectomy for childhood stroke (Save ChildS Pro): an international, multicentre, prospective registry study
Peter B. Sporns,Kartik Bhatia,Todd Abruzzo,Lisa Pabst,Stuart Fraser,Melissa G. Chung,Warren Lo,Ahmed E. Othman,Sebastian Steinmetz,Ulf Jensen‐Kondering,Stefan Schob,Daniel Kaiser,Wolfgang Marik,Christina Wendl,Ilka Kleffner,Hans Henkes,Hermann Kraehling,Thi Dan Linh Nguyen‐Kim,René Chapot,Umut Yılmaz,F. Wang,Muhammad Ubaid Hafeez,Flavio Requejo,Nicola Limbucci,Brice Kauffmann,Markus Möhlenbruch,Omid Nikoubashman,Peter D. Schellinger,Patricia Musolino,Ali Alawieh,Jenny L. Wilson,Dominik Grieb,Alexandra S. Gersing,Thomas Liebig,Martin Olivieri,Jaroslava Paulasová Schwabová,Aleš Tomek,Panagiotis Papanagiotou,Grégoire Boulouis,Olivier Naggara,Christine K. Fox,K Orlov,A. A. Kuznetsova,Carmen Parra‐Farinas,Prakash Muthusami,Robert W. Regenhardt,Adam A. Dmytriw,Tanja Burkard,Mesha Martinez,Daniel Brechbühl,Maja Steinlin,Lisa R. Sun,Ameer E Hassan,André Kemmling,Sarah Lee,Heather J. Fullerton,Jens Fiehler,Marios‐Nikos Psychogios,Moritz Wildgruber +58 more
TL;DR: This international registry study of 208 children with stroke found that endovascular thrombectomy improved functional outcomes compared to best medical treatment, with a significant difference in median modified Rankin Scale scores at 90 days post-stroke.
6
Epidemiology, causes, and morbidities of stroke in the young
Anna M Janas,Megan Barry,Sarah Lee +2 more
TL;DR: Perinatal and childhood strokes are important causes of neurological morbidity, and prospective research studies on epidemiology, causes, and outcomes remain limited, highlighting the need for continued multisite collaborations.
4
Pediatric Interventional Neuroradiology: Opportunities and Challenges
TL;DR: Pediatric interventional neuroradiology (PINR) is a relatively new field of diagnostic and therapeutic care in the pediatric population that has seen considerable advances in recent decades as discussed by the authors .
Global, Regional, and National Burdens of Stroke in Children and Adolescents From 1990 to 2019: A Population-Based Study.
Hao Sun,Bing Ma,Chenye Jin,Zhenning Li,Xinying Song,Yifan Bu,Tingting Liu,Xu Han,Xue Yang,Kaijie Yang,Dongchu Xu,Jing Zhang,Yongze Li +12 more
TL;DR: The global burden of stroke in children and adolescents has increased, with a substantial decrease in YLLs and an increase in incidence.
2
Arterial Ischemic Stroke in Children
Nevena Fileva,Marta Bertamino,Domenico Tortora,Mariasavina Severino +3 more
TL;DR: Arterial ischemic stroke in children has high mortality and disability rates, with distinct risk factors and causes, including congenital heart disease, cervical arterial dissection, and intracranial arteriopathies, necessitating tailored diagnostic and treatment protocols.
2
References
Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials
Mayank Goyal,Bijoy K Menon,Wim H. van Zwam,Diederik W.J. Dippel,Peter Mitchell,Andrew M. Demchuk,Antoni Dávalos,Charles B. L. M. Majoie,Aad van der Lugt,Maria Angeles De Miquel,Geoffrey A. Donnan,Yvo B.W.E.M. Roos,Alain Bonafe,Reza Jahan,Hans-Christoph Diener,Lucie A. van den Berg,Elad I. Levy,Olvert A. Berkhemer,Vitor Mendes Pereira,Jeremy L. Rempel,Mónica Millán,Stephen M. Davis,Daniel Roy,John Thornton,Luis San Roman,Marc Ribo,Debbie Beumer,Bruce Stouch,Scott Brown,Bruce C.V. Campbell,Robert J. van Oostenbrugge,Jeffrey L. Saver,Michael D. Hill,Tudor G Jovin +33 more
TL;DR: Endovascular thrombectomy is of benefit to most patients with acute ischaemic stroke caused by occlusion of the proximal anterior circulation, irrespective of patient characteristics or geographical location, and will have global implications on structuring systems of care to provide timely treatment.
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Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct.
Raul G Nogueira,Ashutosh P Jadhav,Diogo C Haussen,Alain Bonafe,Ronald F. Budzik,Parita Bhuva,Dileep R. Yavagal,Marc Ribo,Christophe Cognard,Ricardo A. Hanel,Cathy A. Sila,Ameer E Hassan,Mónica Millán,Elad I. Levy,Peter Mitchell,Michael Chen,Joey English,Qaisar A. Shah,Frank L. Silver,Vitor Mendes Pereira,Brijesh P Mehta,Blaise Baxter,Michael G. Abraham,Pedro Cardona,Erol Veznedaroglu,Frank R Hellinger,Lei Feng,Jawad F. Kirmani,Demetrius K. Lopes,Brian T. Jankowitz,Michael Frankel,Vincent Costalat,Nirav Vora,Albert J Yoo,Amer M. Malik,Anthony J. Furlan,Marta Rubiera,Amin Aghaebrahim,Jean-Marc Olivot,Wondwossen G Tekle,Ryan K. Shields,Todd Graves,Roger J. Lewis,Wade S. Smith,David S Liebeskind,Jeffrey L. Saver,Tudor G Jovin +46 more
TL;DR: Among patients with acute stroke who had last been known to be well 6 to 24 hours earlier and who had a mismatch between clinical deficit and infarct, outcomes for disability at 90 days were better with thrombectomy plus standard care than with standard care alone.
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European Stroke Organization Guidelines for the Management of Intracranial Aneurysms and Subarachnoid Haemorrhage
Thorsten Steiner,Seppo Juvela,Andreas Unterberg,Carla S. Jung,Michael Forsting,Gabriel J.E. Rinkel +5 more
TL;DR: Ruptured intracranial aneurysm with a high rate of subsequent complications is a serious disease needing prompt treatment in centres having high quality of experience of treatment for these patients, and practical, evidence-based advice is provided for the management of patients with intrac Cranium with or without rupture.
International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion
Andrew J. Molyneux,Richard S. C. Kerr,Ly-Mee Yu,Mike Clarke,Mary Sneade,Julia A. Yarnold,Peter Sandercock +6 more
TL;DR: In patients with ruptured intracranial aneurysms suitable for both treatments, endovascular coiling is more likely to result in independent survival at 1 year than neurosurgical clipping; the survival benefit continues for at least 7 years.
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A proposed grading system for arteriovenous malformations.
TL;DR: A simple, broadly applicable grading system that is designed to predict the risk of morbidity and mortality attending the operative treatment of specific AVM's is proposed and has demonstrated its correlation with the incidence of postoperative neurological complications.
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