Characterization of overall ceramide species in human stratum corneum.
Yoshinori Masukawa,Hirofumi Narita,Eri Shimizu,Naoki Kondo,Yoshiya Sugai,Tsuyoshi Oba,Rika Homma,Junko Ishikawa,Yutaka Takagi,Takashi Kitahara,Yoshinori Takema,Katsumi Kita +11 more
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TL;DR: Overall CER species in human stratum corneum are characterized and a new CER class consisting of α-hydroxy fatty acid and dihydrosphingosine moieties is discovered, in addition to the 10 classes generally known.
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About: This article is published in Journal of Lipid Research. The article was published on 01 Jul 2008. and is currently open access.
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Citations
A lipidome atlas in MS-DIAL 4.
Hiroshi Tsugawa,Kazutaka Ikeda,Mikiko Takahashi,Aya O. Satoh,Yoshifumi Mori,Haruki Uchino,Nobuyuki Okahashi,Yutaka Yamada,Ipputa Tada,Paolo Bonini,Yasuhiro Higashi,Yozo Okazaki,Zhiwei Zhou,Zheng-Jiang Zhu,Jeremy P. Koelmel,Jeremy P. Koelmel,Tomas Cajka,Oliver Fiehn,Kazuki Saito,Masanori Arita,Makoto Arita,Makoto Arita +21 more
TL;DR: A comprehensive lipidome atlas with retention time, collision cross-section and tandem mass spectrometry information is presented and mass spectral fragmentations of lipids across 117 lipid subclasses are presented in a lipidomeAtlas.
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The important role of stratum corneum lipids for the cutaneous barrier function
TL;DR: An overview of the reported SC lipid composition and organization mainly focusing on healthy and diseased human skin is provided and an overview on the relation between lipid modulations and the impaired skin barrier function is provided.
514
Very long-chain fatty acids: elongation, physiology and related disorders
TL;DR: The molecular mechanism of FA elongation and the responsible enzymes in mammals and yeast, as well as VLCFA-related disorders in human are described.
Stratum Corneum Lipids: Their Role for the Skin Barrier Function in Healthy Subjects and Atopic Dermatitis Patients.
TL;DR: Some major changes in epidermal lipid biosynthesis in patients with AD and other related skin diseases are discussed, and how inflammation has a deteriorating effect on the SC lipids and SC biosynthesis.
317
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