Characteristics of human mononuclear phagocytes.
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TL;DR: In this study human mononuclear phagocytes from the bone marrow, peripheral blood monocytes, and tissue macrophages from the skin and the peritoneal cavity were studied with respect to their morphological, cytochemical, and functional characteristics, cell surface receptors, and 3H-thymidine incorporation in vitro.
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About: This article is published in Blood. The article was published on 01 Aug 1979. and is currently open access. The article focuses on the topics: Mononuclear phagocyte system & Monoblast.
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Citations
Mb1, a plasma membrane antigen selectively expressed by U-937 cells
Andrea Biondi,Andrea Biondi,Andrea Biondi,Janice A. Roach,Janice A. Roach,Janice A. Roach,James D. Griffin,James D. Griffin,James D. Griffin,Robert F. Todd,Robert F. Todd,Robert F. Todd +11 more
TL;DR: A murine monoclonal antibody that identifies an antigen, Mb1, found on the surface of U-937 is developed, and its degree of expression relates to the state of cellular differentiation.
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Effect of major surgery on neutrophil chemotaxis and actin polymerization in neonates and children
C. Merry,Prem Puri,Denis J. Reen +2 more
TL;DR: The data suggest that PMN chemotactic function is resistant to the stress of uncomplicated major surgery in neonates and children.
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Phagocytic cells in the human inflammatory response.
TL;DR: These techniques for studying neutrophils and monocytes in skin abrasions and a simple assay of phagocytic and bactericidal function are suitable for inclusion in the early screening of individuals who have repeated bacterial infections.
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Amplification of the polyclonal activation of human T cells. I. Null-cell products promote the polyclonal proliferation of T cells.
TL;DR: The synergistic effect observed between T and Null cells is not due to the promotion of Null- cell proliferation by T -cell products but can be accounted for by diffusible Null-cell products enhancing the process of T lymphocyte activation by mitogens.
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Comparison of the in vivo and in vitro proliferation of monoblasts, promonocytes, and the macrophage cell line J774.
R. Van Furth,Th. J. L. M. Goud,J.W.M. van der Meer,A. Blussé van Oud Alblas,M. M. C. Diesselhoff-Den Dulk,M. Schadewijk-Nieuwstad +5 more
TL;DR: The morphological, cytochemical and functional characteristics of all these kinds of cells, as well as their proliferative behavior in vivo and in vitro, show great similarity, although there are also distinct differences.
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References
The origin and kinetics of mononuclear phagocytes
Ralph van Furth,Zanvil A. Cohn +1 more
TL;DR: It was concluded that the rapidly dividing mononuclear phagocytes of the bone marrow, called promonocytes, are the progenitor cells of the monocytes and give rise to peritoneal macrophages.
•Journal Article
The mononuclear phagocyte system: a new classification of macrophages, monocytes, and their precursor cells
TL;DR: Inclusion of cells in the "mononuclear phagocyte system" is based on similarities in the morphology, function, origin, and kinetics of the phagocytes, and reticular cells, dendritic cells, endothelial cells, and fibroblasts (fibrocytes) are excluded.
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Brief Report: Simplified Myeloperoxidase Stain Using Benzidine Dihydrochloride
Leonard S. Kaplow,Charlotte Ladd +1 more
TL;DR: A method is described for demonstrating leukocyte peroxidase activity in which benzidine dihydrochloride is used as the indicator compound instead of the more commonly used but potentially more hazardous benzidine base.
737
Studies on the mechanism of phagocytosis. I. Requirements for circumferential attachment of particle-bound ligands to specific receptors on the macrophage plasma membrane.
TL;DR: Results indicate that attachment of a particle to specific receptors on the macrophage plasma membrane is not sufficient to trigger ingestion of that particle, and that ingestion requires the sequential, circumferential interaction of particle-bound ligands with specific plasma membrane receptors not involved in the initial attachment process.