There is paucity of knowledge on the histological features of the intestinal mucosa in malnourished adults of Bangladesh. The purpose of the study was to explore the histological features of the intestinal mucosa in malnourished adults of Bangladesh and to compare the findings with their well-nourished counterparts. 64 adults (37 malnourished with body mass index, BMI   18.5 kg/m2) from the Bangladesh Environmental Enteric Dysfunction (BEED) study, who underwent upper-gastrointestinal endoscopy, were selected for this study. With a view to address the association of environmental enteric dysfunction (EED) with malnutrition, upper-gastrointestinal endoscopy was performed and mucosal biopsies from the distal duodenum were studied for histopathology. Villous height, crypt depth, and presence of inflammatory infiltrates in lamina propria were investigated. Bivariate analysis was performed to quantify the relation between malnutrition and the histological features. About 95% adults, irrespective of nutritional status, were diagnosed to have chronic non-specific duodenitis on histopathology. Malnourished adults suffered significantly more from chronic active duodenitis compared to their well-nourished counterparts (p = 0.003). Malnourished adults also had significantly higher frequency of subtotal villous atrophy, crypt hyperplasia and marked cellular infiltration in the lamina propria than the healthy controls (p < 0.05).

/pdf/alterations-in-the-histological-features-of-the-intestinal-597lg1estx.pdf

Alterations in the histological features of the intestinal mucosa in malnourished adults of Bangladesh.

............................................................................................................ XVIII CHAPTER ONE ..............................................................................................................

Nutrient profile, prebiotic potential of edible cricket, and effect of cricket-based porridge on growth, haemoglobin and fatty acid levels of school children

/pdf/chapter-one-environmental-enteric-dysfunction-eed-background-442n8qle8l.pdf

Chapter One. Environmental enteric dysfunction (EED) background

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Chapter One. Environmental enteric dysfunction (EED) background

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Alterations in the histological features of the intestinal mucosa in malnourished adults of Bangladesh.

Nutrient profile, prebiotic potential of edible cricket, and effect of cricket-based porridge on growth, haemoglobin and fatty acid levels of school children